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TrkA NGF receptor expression by non-cholinergic thalamic neurons
NeuroReport, 1993Expression of the trkA receptor for nerve growth factor was analyzed by mRNA in situ hybridization in the telencephalon and diencephalon in adult rats. Two densely packed populations expressing trkA mRNA were detected in the thalamus, in the paraventricular thalamic nucleus anterior and reuniens thalamic nucleus.
J L, Venero, F, Hefti
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TrkA as a life and death receptor: receptor dose as a mediator of function.
Cancer research, 2002Nerve growth factor (NGF) has been implicated as both an inhibitor and an inducer of apoptosis. Binding of NGF to its TrkA receptor is generally considered to have an antiapoptotic effect. However, neuroblastomas that overexpress TrkA have a good prognosis and frequently regress by apoptosis either spontaneously or after chemotherapeutic treatment ...
Chaohua, Yan +3 more
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Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 2001
Nerve growth factor (NGF) and its main low- (p75LNGFR) and high-affinity (TrkA) receptors have been found in the vertebrate thymus, thus suggesting they are involved in the control of thymic function. However, its role in this organ is poorly known. In the present study we used combined morphological and immunohistochemical techniques to analyze the ...
GARCIA, Olivia +6 more
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Nerve growth factor (NGF) and its main low- (p75LNGFR) and high-affinity (TrkA) receptors have been found in the vertebrate thymus, thus suggesting they are involved in the control of thymic function. However, its role in this organ is poorly known. In the present study we used combined morphological and immunohistochemical techniques to analyze the ...
GARCIA, Olivia +6 more
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Development and Uses of Small Molecule Ligands of TrkA Receptors
1998Nerve Growth Factor (NGF), is a polypeptide that elicits widespread biological effects via interaction with a tyrosine kinase receptor termed TrkA (Kaplan et al., 1991). NGF a member of the neurotrophin (NT) family of growth factors is responsible for the survival, differentiation and maintenance of specific sensory, sympathetic and cholinergic ...
Lynne LeSauteur +3 more
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Reactome - a curated knowledgebase of biological pathways, 2007
S Nasi, D Annibali
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S Nasi, D Annibali
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Journal of neurochemistry, 2011
The work was supported by the Instituto de Salud Carlos III – Ministerio de Sanidad y Consumo (FIS) (PI04/2537 and PS09/ 00140) to ML, the Ministry of Science and Innovation of Spain (SAF2005-02197 and SAF2008-02271) to DS and SAF2007-60287, Programa de Suport a Grups de Recerca from the Government of Catalonia (SGR2005-00628) and Ciberned (CB06/05 ...
Georgieva, Maya V. +4 more
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The work was supported by the Instituto de Salud Carlos III – Ministerio de Sanidad y Consumo (FIS) (PI04/2537 and PS09/ 00140) to ML, the Ministry of Science and Innovation of Spain (SAF2005-02197 and SAF2008-02271) to DS and SAF2007-60287, Programa de Suport a Grups de Recerca from the Government of Catalonia (SGR2005-00628) and Ciberned (CB06/05 ...
Georgieva, Maya V. +4 more
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TrkA neurogenic receptor regulates differentiation of neuroblastoma cells.
Oncogene, 1995We examined events associated with neuronal differentiation of neuroblastoma cell line SH-SY5Y. Treatment with nerve growth factor (NGF) and aphidicolin, an inhibitor of DNA polymerases alpha and delta, induces terminal differentiation of SH-SY5Y cells.
W, Poluha, D K, Poluha, A H, Ross
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Lack of TrkA (Nerve Growth factor receptor) expression in keratoconus
2004http://hdl.handle.net/20.500.11768 ...
Lambiase A +6 more
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