Inhibition of receptor activator of nuclear factor kappa-B ligand pathway for the management of aggressive osteosarcoma. [PDF]
Ann Transl Med, 2016 Receptor activator of nuclear factor kappa-B ligand (RANKL) is a member of the tumor necrosis factor receptor superfamily and is considered the most important factor for osteoclastogenesis. RANKL is encoded by a gene, which is found at chromosome 13q14 and is expressed mainly by osteocytes, activated T-cells and bone marrow stromal cells.
Panagiotidis I, Christoulas D, Terpos E.
europepmc +5 more sources
Isoliquiritigenin Inhibits Metastatic Breast Cancer Cell-induced Receptor Activator of Nuclear Factor Kappa-B Ligand/Osteoprotegerin Ratio in Human Osteoblastic Cells. [PDF]
J Cancer Prev, 2015 Bone destruction induced by the metastasis of breast cancer cells is a frequent complication that is caused by the interaction between cancer cells and bone cells.
Lee SK +4 more
europepmc +2 more sources
Expression of receptor activator of nuclear factor kappa B ligand in bladder cancer [PDF]
International Journal of Urology, 2018 Mari Ohtaka +6 more
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Yukmijihwang-Tang Suppresses Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL)-Induced Osteoclast Differentiation and Prevents Ovariectomy (OVX)-Mediated Bone Loss. [PDF]
Molecules, 2021 Han SY, Kim YK.
europepmc +3 more sources
Receptor activator of nuclear factor kappa B ligand [PDF]
Springer Reference Medizin, 2019 H. Haubeck
semanticscholar +2 more sources
Indian J Endocrinol Metab, 2014 Introduction: Osteoporosis represents the second most common cause of endocrinopathy in patients with beta thalassemia major (BTM). Some drugs proved effective to reduce vertebral and non-vertebral fracture risk.
Yassin MA +6 more
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Receptor activator of nuclear factor kappa-B ligand (RANKL) but not sclerostin or gene polymorphisms is related to joint destruction in early rheumatoid arthritis. [PDF]
Clin Rheumatol, 2017 Boman A +4 more
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Angiotensin II Induces Aortic Rupture and Dissection in Osteoprotegerin‐Deficient Mice
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background The biological mechanism of action for osteoprotegerin, a soluble decoy receptor for the receptor activator of nuclear factor‐kappa B ligand in the vascular structure, has not been elucidated.
Toshihiro Tsuruda +12 more
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Exploring new pathways in endocrine-resistant breast cancer
Exploration of Targeted Anti-tumor Therapy, 2022 The most common breast cancer (BC) subtypes are hormone-dependent, being either estrogen receptor-positive (ER+), progesterone receptor-positive (PR+), or both, and altogether comprise the luminal subtype.
Inês Soares de Pinho +6 more
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Effect of lipopolysaccharide derived from surabaya isolates of Actinobacillus actinomycetemcomitans on alveolar bone destruction [PDF]
Veterinary World, 2018 Background: Actinobacillus actinomycetemcomitans' lipopolysaccharide (LPS) has a high virulence factor. It interacts with serum protein through receptors on the epithelial cell surface, thereby increasing both interleukin (IL)-1β, and IL-6 which results ...
Rini Devijanti Ridwan +3 more
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