Results 1 to 10 of about 59,132 (205)

Receptor for Advanced Glycation End Products and Its Involvement in Inflammatory Diseases [PDF]

International Journal of Inflammation, 2013
The receptor for advanced glycation end products (RAGE) is a transmembrane receptor of the immunoglobulin superfamily, capable of binding a broad repertoire of ligands. RAGE-ligands interaction induces a series of signal transduction cascades and lead to
Yaw Kuang Chuah, Rusliza Basir, Herni Talib, Tung Hing Tie, Norshariza Nordin   +4 more
doaj   +4 more sources

Advanced glycation end products induce peroxisome proliferator-activated receptor γ down-regulation-related inflammatory signals in human chondrocytes via Toll-like receptor-4 and receptor for advanced glycation end products. [PDF]

PLoS ONE, 2013
Accumulation of advanced glycation end products (AGEs) in joints is important in the development of cartilage destruction and damage in age-related osteoarthritis (OA).
Ying Ju Chen, Meei Ling Sheu, Keh Sung Tsai, Rong Sen Yang, Shing Hwa Liu   +4 more
doaj   +5 more sources

Receptor for advanced glycation end-products (RAGE) mediates phagocytosis in nonprofessional phagocytes [PDF]

Communications Biology, 2022
The multiligand receptor RAGE (receptor for advanced glycation end-products) mediates phagocytosis in non-professional phagocytes (NPPs), for example through the use of RNA fragments as ligands for internalization.
Yan Yang, Guoyu Liu, Feng Li, Lucas B. Carey, Changjin Sun, Kaiping Ling, Hiroyuki Tachikawa, Morihisa Fujita, Xiao-Dong Gao, Hideki Nakanishi   +9 more
doaj   +2 more sources

Receptor for Advanced Glycation End Products (RAGE): A Pivotal Hub in Immune Diseases [PDF]

Molecules, 2022
As a critical molecule in the onset and sustainment of inflammatory response, the receptor for advanced glycation end products (RAGE) has a variety of ligands, such as advanced glycation end products (AGEs), S100/calcium granule protein, and high ...
Qing Yue, Yu Song, Zi Liu, Lin Zhang, Ling Yang, Jinlong Li   +5 more
doaj   +2 more sources

The effect of Galega officinalis L. extract on the content of the advanced glycation end products and their receptors in rat leukocytes under experimental diabetes mellitus

Біологічні студії, 2021
Background. Diabetes mellitus intensifies non-enzymatic glycosylation (glycation) of biomolecules under conditions of chronic hyperglycemia and facilitates accumulation of advanced glycation end products.
Kh. Ye. Furtak, H. Ya. Hachkova, N. O. Sybirna   +2 more
doaj   +1 more source

Expression of advanced glycation end products and receptors in gingival tissues of patients with noninsulin-dependent diabetes mellitus-associated periodontitis

Journal of Dental Sciences, 2023
Background/purpose: Advanced glycation end products (AGEs) are known to accumulate in the periodontal tissues of patients with diabetes mellitus (DM). Through this study, we aimed to investigate the distribution of AGEs and the receptor of AGEs (RAGE) in
Ya-Han Chang, Chen-Ling Huang, An-Tsz Hsieh, Chia-Ai Jao, Hsein-Kun Lu   +4 more
doaj   +1 more source

Non-enzymatic glycoxidation linked with nutrition enhances the tumorigenic capacity of prostate cancer epithelia through AGE mediated activation of RAGE in cancer associated fibroblasts

Translational Oncology, 2022
The molecular implications of food consumption on cancer etiology are poorly defined. The rate of nutrition associated non-enzymatic glycoxidation, a reaction that occurs between reactive carbonyl groups on linear sugars and nucleophilic amino, lysyl and
Bradley A. Krisanits, Pamela Woods, Lourdes M. Nogueira, Demarcus D. Woolfork, Courtney E. Lloyd, Andrew Baldwin, Callan C. Frye, Kendell D. Peterson, Sean D. Cosh, Qi-Jin Guo, Laura S. Spruill, Michael B. Lilly, Kristi Helke, Hong Li, George S. Hanna, Mark T. Hamann, Courtney Thomas, Mahtabuddin Ahmed, Monika B. Gooz, Victoria J. Findlay, David P. Turner   +20 more
doaj   +1 more source

The Role of Advanced Glycation End Products in Diabetic Vascular Complications [PDF]

Diabetes & Metabolism Journal, 2018
In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues.
Sang Youl Rhee, Young Seol Kim
doaj   +1 more source

Clearance kinetics and matrix binding partners of the receptor for advanced glycation end products [PDF]

, 2014
Elucidating the sites and mechanisms of sRAGE action in the healthy state is vital to better understand the biological importance of the receptor for advanced glycation end products (RAGE).
A Bierhaus, AL Miller, AM Schmidt, B Rippe, C Cheng, C Chuong, CN Pace, D Frommhold, DI Sternberg, DS Pisetsky, G Marsche, H Fehrenbach, H Vlassara, H Vlassara, H Zhang, HC Volz, J Brett, J Steiner, J Xie, Jan J. Enghild, JH Boyd, JL Wautier, JM Englert, JM Englert, JR Klune, Judson M. Englert, K Dahlin, K Kataoka, KC Sourris, Lasse Ramsgaard, Lauren T. Crum, LE Hanford, Louis J. Sparvero, M Neeper, M Shirasawa, MA Hofmann, Michael T. Lotze, MT Goova, N Demling, Neale S. Mason, P Andrews, P Teismann, Pavle S. Milutinovic, R Pullerits, R Ramasamy, RH Hastings, RH Hastings, RM Effros, S Du Yan, S Mizumoto, S Muhammad, S Zeng, T Do, T Wendt, TA John, Tim D. Oury, William R. Abrams, Y Abdiche, Z Sarkany   +58 more
core   +8 more sources

Advanced Glycation End Products, Soluble Receptor for Advanced Glycation End Products, and Risk of Colorectal Cancer [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2011
Abstract Background: Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE–ligand engagement ...
Li, Jiao, Philip R, Taylor, Stephanie J, Weinstein, Barry I, Graubard, Jarmo, Virtamo, Demetrius, Albanes, Rachael Z, Stolzenberg-Solomon   +6 more
openaire   +2 more sources