Results 1 to 10 of about 78,662 (379)

Advanced Glycation End Products Acutely Impair Ca2+ Signaling in Bovine Aortic Endothelial Cells [PDF]

, 2013
Post-translational modification of proteins in diabetes, including formation of advanced glycation end products (AGEs) are believed to contribute to vascular dysfunction and disease.
Alicia J. Jenkins, Andrzej S. Januszewski, Bronwyn E. Brown, Michael A. Hill, Nadim Naser, Timothy V. Murphy   +5 more
core   +2 more sources

The usefulness of soluble receptor for advanced glycation end-products in the identification of COPD frequent exacerbator phenotype

International Journal of COPD, 2018
Joanna Miłkowska-Dymanowska,1,2,* Adam J Białas,1,2,* Karolina Szewczyk,1 Zofia Kurmanowska,1 Paweł Górski,1,2 Wojciech J Piotrowski1,2 1Department of Pneumology and Allergy, Medical University of Łódź, Łódź, Poland; 2Healthy Ageing
Miłkowska-Dymanowska J, Białas AJ, Szewczyk K, Kurmanowska Z, Górski P, Piotrowski WJ   +5 more
doaj  

Mdia1 is Crucial for Advanced Glycation End Product-Induced Endothelial Hyperpermeability

Cellular Physiology and Biochemistry, 2018
Background/Aims: Disruption of endothelial barrier integrity in response to advanced glycation end products (AEGs) stimulation contributes to vasculopathy associated with diabetes mellitus. Mammalian diaphanous-related formin (mDia1) has been reported to
Xiaoyan Zhou, Jie Weng, Jing Xu, Qiulin Xu, Weiju Wang, Weijin Zhang, Qiaobing Huang, Xiaohua Guo   +7 more
doaj   +1 more source

Plasma Levels of Pentosidine, Carboxymethyl-Lysine, Soluble Receptor for Advanced Glycation End Products, and Metabolic Syndrome: The Metformin Effect

Disease Markers, 2016
Metabolic syndrome (MetS) is considered one of the most important public health problems. Several and controversial studies showed that the role of advanced glycation end products (AGEs) and their receptor in the development of metabolic syndrome and ...
Mohamed Haddad, I. Knani, H. Bouzidi, O. Berriche, M. Hammami, M. Kerkeni   +5 more
semanticscholar   +1 more source

Serum markers of bone fragility in type-2 diabetes mellitus [PDF]

, 2019
Patients with type-2 diabetes mellitus (T2DM) have normal or increased bone mineral density (BMD) but despite that, they are characterized by an increased hip and vertebral fracture risk that involves the alteration of bone quality and not the reduction ...
Dănciulescu Miulescu, Rucsandra, Guja, Loreta, Ochiana, Lavinia Claudia, Ungurianu, Anca, Șeremet, Oana Cristina, Ștefănescu, Emil   +5 more
core   +1 more source

Circulating soluble receptor for advanced glycation end product: Cross-sectional associations with cardiac markers and subclinical vascular disease in older men with and without diabetes. [PDF]

, 2017
BACKGROUND AND AIMS: The soluble receptor for advanced glycation end products (sRAGE) has been implicated in diabetic vascular complications. We have examined the association between sRAGE and cardiac markers [NT-proBNP and cardiac troponin T (cTnT)] and
Bower, Cauwenberghs, Chiang, Chirinos, Colhoun, Dijk, Elizabeth A. Ellins, Emberson, Falcone, Fujisawa, Hanssen, Hartog, Hudson, Janner, Julian P.J. Halcox, Kizer, Lampe, Laurent, Lazo, Lennon, Levey, Lindsey, Lindsey, Mayer, McMurray, Meerwaldt, Nakamura, Naveed Sattar, Nin, Olia Papacosta, Paul Welsh, Peter H. Whincup, Ramsay, Raposeiras-Roubín, S. Goya Wannamethee, Selvin, Semba, Semba, Semba, Sharman, Thomas, Thomas, van den Oord, Vlachopoulos, Walker, Wang, Wannamethee, Weber, Yoon   +48 more
core   +2 more sources

Bone-Targeting Endogenous Secretory Receptor for Advanced Glycation End Products Rescues Rheumatoid Arthritis

Molecular Medicine, 2013
Rheumatoid arthritis (RA) is a chronic inflammatory synovitis that leads to the destruction of bone and cartilage. The receptor for advanced glycation end products (RAGE) is a multiligand membrane-bound receptor for high-mobility group box-1 (HMGB1 ...
Tatsuo Takahashi, Sayaka Katsuta, Yusuke Tamura, Nozomi Nagase, Keita Suzuki, Masaaki Nomura, Shunji Tomatsu, Ken-ichi Miyamoto, Shinjiro Kobayashi   +8 more
doaj   +1 more source

The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs

Biochemistry, 2014
Diabetes-induced hyperglycemia increases the extracellular concentration of methylglyoxal. Methylglyoxal-derived hydroimidazolones (MG-H) form advanced glycation end products (AGEs) that accumulate in the serum of diabetic patients.
Jing Xue, Rashmi Ray, D. Singer, David Böhme, D. Burz, V. Rai, Ralf Hoffmann, A. Shekhtman   +7 more
semanticscholar   +1 more source

Transcriptional regulation of endothelin-1 expression by advanced glycation end-products in human aortic endothelium is mediated via NF-kappaΒ and AP-1 [PDF]

, 2012
Advanced Glycation End-products (AGEs) are produced by the non-enzymatic glycation of proteins, lipids and nucleic acids, resulting in an overload of highly reactive molecules of endogenous or exogenous (dietary) origin.
Adamopoulos, Christos, Dalagiorgou, Georgia, Diamanti-Kandarakis, Evanthia, Gargalionis, Antonios N., Kandaraki, Eleni A., Papavassiliou, Athanasios G., Piperi, Christina   +6 more
core  

Soluble receptor for advanced glycation end products as an indicator of pulmonary vascular injury after cardiac surgery [PDF]

, 2013
Background: Cardiac surgery is frequently complicated by an acute vascular lung injury and this may be mediated, at least in part, by the (soluble) receptor for advanced glycation end products (sRAGE).Methods: In two university hospital intensive care ...
Beishuizen, A. (Auke), Cornet, A.D. (Alexander), Groeneveld, A.B.J. (Johan), Juffermans, N.P. (Nicole), Kuipers, M.T. (Maria), Schultz, M.J. (Marcus), Tuinman, S. (Sietske), Vlaar, A.P.J. (Alexander)   +7 more
core   +2 more sources