Association of advanced glycation end products in Dupuytren disease
Background Advanced glycation end products are associated with aging, hyperglycemia, and oxidative stress. Accumulation of advanced glycation end products can cause various pathological conditions; however, the association of Dupuytren’s disease with ...
Fumiaki Takase +6 more
doaj +1 more source
Thiazolidinediones Reduce Endothelial Expression of Receptors for Advanced Glycation End Products [PDF]
Advanced glycation end products (AGEs) are critically involved in atherogenesis in diabetes by binding to receptors for AGE (RAGEs) in vascular cells, thus inducing the expression of proinflammatory mediators. In animal models, interruption of the AGE-RAGE interaction reduces lesion size and plaque development. Therefore, limiting RAGE expression might
MARX N +10 more
openaire +5 more sources
Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti +3 more
core +5 more sources
Systemic lupus erythematosus (SLE) is characterized by abnormal action of the immune system and a state of chronic inflammation. The disease can cause life-threatening complications.
Agnieszka Nowak +5 more
doaj +1 more source
Oxidative stress, protein glycation and nutrition – interactions relevant to health and disease throughout the lifecycle [PDF]
Protein glycation has been studied for over a century now and plays an important role in disease pathogenesis throughout the lifecycle. Strongly related to diabetic complications, glycation of Hb has become the gold standard method for diabetes diagnosis
American Diabetes +17 more
core +3 more sources
RAGE Signaling in Skeletal Biology [PDF]
PURPOSE OF REVIEW: The receptor for advanced glycation end products (RAGE) and several of its ligands have been implicated in the onset and progression of pathologies associated with aging, chronic inflammation, and cellular stress. In particular, the
Davis, Hannah M. +2 more
core +2 more sources
Retraction: Advanced Glycation End Products Induce Peroxisome Proliferator-Activated Receptor γ Down-Regulation-Related Inflammatory Signals in Human Chondrocytes via Toll-Like Receptor-4 and Receptor for Advanced Glycation End Products. [PDF]
Ying Ju Chen +4 more
doaj +2 more sources
Pharmacologic approaches against advanced glycation end products (ages) in diabetic cardiovascular disease [PDF]
Advanced Glycation End-Products (AGEs) are signaling proteins associated to several vascular and neurological complications in diabetic and non-diabetic patients.
Avtaar Singh, Sanjeet Singh +6 more
core +2 more sources
Elevated hemoglobin glycation index identify non-diabetic individuals at increased risk of kidney dysfunction [PDF]
Hemoglobin glycation index (HGI), calculated as the difference between the observed value of HbA1 and the predicted HbA1c based on plasma glucose concentration, is a measure of the individual tendency toward non-enzymatic hemoglobin glycation which has ...
Andreozzi, F +6 more
core +3 more sources
Introduction High mobility group box 1 is a versatile protein involved in gene transcription, extracellular signaling, and response to inflammation. Extracellularly, high mobility group box 1 binds to several receptors, notably the receptor for advanced ...
Austin Nguyen +4 more
doaj +1 more source

