Results 31 to 40 of about 78,662 (379)

The Receptor for Advanced Glycation End Products (RAGE) and the Lung [PDF]

Journal of Biomedicine and Biotechnology, 2010
The receptor for advanced glycation end products (RAGE) is a member of the immunoglobulin superfamily of cell surface molecules. As a pattern-recognition receptor capable of binding a diverse range of ligands, it is typically expressed at low levels under normal physiological conditions in the majority of tissues.
BUCKLEY, STEPHEN, EHRHARDT, CARSTEN
openaire   +4 more sources

Clearance kinetics and matrix binding partners of the receptor for advanced glycation end products [PDF]

, 2014
Elucidating the sites and mechanisms of sRAGE action in the healthy state is vital to better understand the biological importance of the receptor for advanced glycation end products (RAGE).
A Bierhaus, AL Miller, AM Schmidt, B Rippe, C Cheng, C Chuong, CN Pace, D Frommhold, DI Sternberg, DS Pisetsky, G Marsche, H Fehrenbach, H Vlassara, H Vlassara, H Zhang, HC Volz, J Brett, J Steiner, J Xie, Jan J. Enghild, JH Boyd, JL Wautier, JM Englert, JM Englert, JR Klune, Judson M. Englert, K Dahlin, K Kataoka, KC Sourris, Lasse Ramsgaard, Lauren T. Crum, LE Hanford, Louis J. Sparvero, M Neeper, M Shirasawa, MA Hofmann, Michael T. Lotze, MT Goova, N Demling, Neale S. Mason, P Andrews, P Teismann, Pavle S. Milutinovic, R Pullerits, R Ramasamy, RH Hastings, RH Hastings, RM Effros, S Du Yan, S Mizumoto, S Muhammad, S Zeng, T Do, T Wendt, TA John, Tim D. Oury, William R. Abrams, Y Abdiche, Z Sarkany   +58 more
core   +8 more sources

Advanced Glycation End Products, Soluble Receptor for Advanced Glycation End Products, and Risk of Colorectal Cancer [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2011
Abstract Background: Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE–ligand engagement ...
Stephanie J. Weinstein, Philip R. Taylor, Jarmo Virtamo, Barry I. Graubard, Demetrius Albanes, Li Jiao, Rachael Z. Stolzenberg-Solomon   +6 more
openaire   +3 more sources

Receptor for Advanced Glycation End Products (RAGE) and Mechanisms and Therapeutic Opportunities in Diabetes and Cardiovascular Disease: Insights From Human Subjects and Animal Models

Frontiers in Cardiovascular Medicine, 2020
Obesity and diabetes are leading causes of cardiovascular morbidity and mortality. Although extensive strides have been made in the treatments for non-diabetic atherosclerosis and its complications, for patients with diabetes, these therapies provide ...
Lander Egaña-Gorroño, R. López-Díez, Gautham Yepuri, L. Ramirez, S. Reverdatto, Paul F. Gugger, A. Shekhtman, R. Ramasamy, A. Schmidt   +8 more
semanticscholar   +1 more source

Precipitation of acute coronary syndrome in an interactive association of oxidative stress biomarkers with soluble receptor for advanced glycation end-products

Journal of Taibah University for Science, 2023
Background: As a repercussion of oxidative stress, reactive oxygen species augment the biochemical reaction of amino and carbohydrate groups of proteins, thus forming oxidative products known as Advanced Glycation End-products (AGEs), associated with ...
Aamenah Malik, Maira Mahmood, M. Mushtaq, Hira Sohail, M. Talib, Farhat Ijaz   +5 more
semanticscholar   +1 more source

Retraction: Advanced Glycation End Products Induce Peroxisome Proliferator-Activated Receptor γ Down-Regulation-Related Inflammatory Signals in Human Chondrocytes via Toll-Like Receptor-4 and Receptor for Advanced Glycation End Products. [PDF]

PLoS ONE
Ying Ju Chen, Meei Ling Sheu, Keh Sung Tsai, Rong Sen Yang, Shing Hwa Liu   +4 more
doaj   +2 more sources

Role of advanced glycation end products on vascular smooth muscle cells under diabetic atherosclerosis

Frontiers in Endocrinology, 2022
Atherosclerosis (AS) is a chronic inflammatory disease and leading cause of cardiovascular diseases. The progression of AS is a multi-step process leading to high morbidity and mortality. Hyperglycemia, dyslipidemia, advanced glycation end products (AGEs)
Lin Mao, Ruili Yin, Longyan Yang, Dong Zhao   +3 more
doaj   +1 more source

Participation of the Receptor for Advanced Glycation End Products in Efferocytosis [PDF]

The Journal of Immunology, 2011
Abstract Clearance of apoptotic cells by macrophages and other phagocytic cells, called efferocytosis, is a central process in the resolution of inflammation. Although the receptor for advanced glycation end products (RAGE) has been shown to participate in a variety of acute and chronic inflammatory processes in the lungs and other ...
Andressa de Freitas, Edward Abraham, Arnaud Friggeri, Sami Banerjee, Subrata K. Biswas, Gang Liu, Angelika Bierhaus   +6 more
openaire   +3 more sources

Prevention of Protein Glycation by Natural Compounds [PDF]

, 2015
Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of organisms. It can be expected that inhibition of glycation may prolong the lifespan.
Bartosz, Grzegorz, Sadowska-Bartosz, Izabela   +1 more
core   +5 more sources

Pathological Role of Receptor for Advanced Glycation End Products in Calcified Aortic Valve Stenosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Aortic stenosis (AS) is highly prevalent in patients with atherosclerotic cardiovascular disease. Advanced glycation end products (AGEs) and the receptor for AGEs (RAGE) play a pivotal role for vascular calcification in atherosclerosis.
Kosuke Saku, Nobuhiro Tahara, Tohru Takaseya, Hiroyuki Otsuka, Kazuyoshi Takagi, Takahiro Shojima, Yusuke Shintani, Yasuyuki Zaima, Satoshi Kikusaki, Tomofumi Fukuda, Atsunobu Oryoji, Yuri Nishino, Takanori Matsui, Tatsuyuki Kakuma, Jun Akiba, Yoshihiro Fukumoto, Sho‐ichi Yamagishi, Hiroyuki Tanaka   +17 more
doaj   +1 more source