Results 191 to 200 of about 107,178 (262)

Mapping the Global Clinical Landscape of Pharmacological Therapies for Heart Failure With Preserved Ejection Fraction: An Analysis Based on ClinicalTrials.gov (2003–2025)

iMetaMed, EarlyView.
This study analyzed 236 heart failure with preserved ejection fraction (HFpEF) pharmacological trials registered on ClinicalTrials.gov from 2003 to 2025, revealing a post‐2016 surge (76.3%), U.S. dominance (58.5%), and prominence of SGLT2 inhibitors/novel therapies (each 13.1%).
Yucheng Hou, Jingwei Zhao, Yuqian Tang, Tan Liu, Zhiao Zhang, Ziheng Wang, Han Shen   +6 more
wiley   +1 more source

Structural and Computational Insights into the Angiotensin II Type 1 Receptor: Advances in Antagonist Design and Implications for Hypertension Therapy (2020-2024). [PDF]

Biomolecules
Chatzipieris FP, Petsas E, Lambrinidis G, Matsoukas JM, Mavromoustakos T.   +4 more
europepmc   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Astrocyte-Neuron Crosstalk in Hypertension: Mechanisms and Therapeutic Significance. [PDF]

Rev Cardiovasc Med
Zhao M, Jia H, Li N.
europepmc   +1 more source

Advances in the Treatment of Autosomal Dominant Polycystic Kidney Disease and Novel Therapeutic Targets. [PDF]

Curr Issues Mol Biol
Zhang W, Sun T, Wang X, Jiang T.
europepmc   +1 more source

Characterization of elevated levels of endometrial renin-angiotensin system components suggest a role in endometrial repair. [PDF]

Front Endocrinol (Lausanne)
Symington TL, Fisher JJ, Zhou W, Dimitriadis E, Lumbers ER, Tooney P, Pringle KG.   +6 more
europepmc   +1 more source

The Role of β-Blockers in the Evolving Treatment Landscape of Resistant Hypertension. [PDF]

Drugs
Masi S, Pathak A, Bruno RM, Brouwers S, Narkiewicz K, Taddei S, Tsioufis K, Kreutz R.   +7 more
europepmc   +1 more source

The role of IP₃R and TRPC3 channels in vasoconstriction and hypertension. [PDF]

Pflugers Arch
Moraes RDA, Alves QL, da Silva LB, de Jesus RLC, Silva DF.   +4 more
europepmc   +1 more source

The Cardioprotective Potential of Marine Venom and Toxins. [PDF]

Toxins (Basel)
Siagian VHM, Nuwarda RF.
europepmc   +1 more source