Results 201 to 210 of about 107,178 (262)

Angiotensin Receptors - Affinity and Beyond

Clinical Science, 2022
Abstract This commentary on the article “Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors” by Sanja Bosnyak et al. (Clini. Sci. (Lond.) (2011) 121(7): 297–303. https://doi.org/10.1042/CS20110036) summarises the main findings of the study, followed by a discussion of the findings and their relevance for
Colin Sumners, Igor Maciel Souza Silva, U. Muscha Steckelings   +2 more
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Angiotensin and angiotensin receptors in cartilaginous fishes

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2001
In mammals, a principal bioactive component of the renin-angiotensin system (RAS), angiotensin II (ANG II), is known to be vasopressor, dipsogenic, a stimulant of adrenocortical secretion and to control glomerular and renal tubular function. Historically, a RAS analogous to that found in mammals was thought to have first evolved in the bony fishes ...
ANDERSON W. G, CERRA, Maria Carmela, WELLS A., TIERNEY M. L., TOTA B., TAKEI Y., HAZON . N.   +6 more
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Tachyphylaxis and angiotensin receptors

General Pharmacology: The Vascular System, 1976
Angiotensin tachyphylaxis was studied in the isolated guinea pig ileum under isometric conditions. 2. In tachyphylactic organs, the initial phasic response to angiotensin was abolished, while the tonic component of the response became faster in its onset and in its reversal (relaxation). 3.
Paiva, T. B., Aboulafia, J., Nouailhetas, VLA, Paiva, ACM   +3 more
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Angiotensin Receptors and Their Antagonists

New England Journal of Medicine, 1996
Angiotensins are peptide hormones derived from the protein precursor angiotensinogen by the sequential actions of proteolytic enzymes (Figure 1). The classic pathway of angiotensin synthesis includes a reaction catalyzed by angiotensin-converting enzyme (ACE), which occurs not only in plasma but also in the kidneys, brain, adrenal glands, ovaries, and ...
T L, Goodfriend, M E, Elliott, K J, Catt
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Angiotensin receptors

Trends in Pharmacological Sciences, 1997
The octapeptide angiotensin II, the potent effector molecule of the renin-angiotensin system, has been implicated in the pathology of hypertension, in cardiovascular diseases like cardiac left ventricular hypertrophy and in structural alterations of the heart such as post-infarct remodelling.The development of highly selective angiotensin II receptor ...
T, Unger, O, Chung, T, Csikos, J, Culman, S, Gallinat, P, Gohlke, S, Höhle, S, Meffert, M, Stoll, U, Stroth, Y Z, Zhu   +10 more
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Angiotensin receptor blockers and angiotensin receptor–neprilysin inhibitors

2022
Abstract This chapter addresses angiotensin receptor blockers (ARBs) and angiotensin receptor–neprilysin inhibitors (ARNIs). ARBs or angiotensin II receptor antagonists were introduced as a potentially superior alternative to an angiotensin converting enzyme (ACE) inhibitor and, later, as a possible addition to an ACE inhibitor.
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The Angiotensin II Receptor and the Actions of Angiotensin II

Journal of Cardiovascular Pharmacology, 1990
Angiotensin II (Ang II) is a potent effector peptide of the renin-angiotensin system that exerts a wide variety of physiological actions on the cardiovascular, renal, endocrine, and central and peripheral nervous systems. Angiotensin exerts its actions by binding to specific receptors in the plasma membrane of various tissues.
M J, Peach, D E, Dostal
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