Results 211 to 220 of about 107,178 (262)

Is the adrenal angiotensin receptor angiotensin II — or angiotensin III like?

Acta Endocrinologica, 1983
Abstract. In order to determine whether the adrenal receptor is primarily directed at angiotensin II (All) or angiotensin III (AIII) the following in vitro experiments were performed examining aldosterone responsiveness in isolated glomerulosa cells.
L M, Braley, A I, Menachery, R H, Underwood, G H, Williams   +3 more
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Angiotensin Receptors and the Vagal System

Clinical and Experimental Hypertension. Part A: Theory and Practice, 1988
Angiotensin II (Ang II) is known to attenuate the vagal component of the baroreflex at both central and peripheral cardiac sites. Ang II receptor binding sites occur in both the nucleus of the solitary tract (NTS), where they are associated with vagal afferent terminals, and in the dorsal motor nucleus of vagus.
A M, Allen, S J, Lewis, A J, Verberne, F A, Mendelsohn   +3 more
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Angiotensin II Receptors in Testes

Endocrinology, 1988
Receptors for angiotensin II (AII) were identified and characterized in testes of rats and several primate species. Autoradiographic analysis of the binding of 125I-labeled [Sar1,Ile8]AII to rat, rhesus monkey, cebus monkey, and human testicular slide-mounted frozen sections indicated specific binding to Leydig cells in the interstitium.
M A, Millan, G, Aguilera
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Angiotensin II Receptor Heterogeneity

American Journal of Hypertension, 1991
The possibility of receptor heterogeneity in the angiotensin II (AII) system has been suggested previously, based on differences in Kd values or sensitivity to thiol reagents. One of our earliest indications was the frequent observation of incomplete inhibition of the binding of AII to adrenal cortical membranes.
William F. Herblin, Andrew T. Chiu, Dale E. McCall, Robert J. Ardecky, David J. Carini, John V. Duncia, Lori J. Pease, Pancras C. Wong, Ruth R. Wexler, Alexander L Johnson, Pieter B.M.W.M. Timmermans   +10 more
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Update on the Angiotensin AT2 Receptor

Current Hypertension Reports, 2012
It is quite well established that activation of the AT(2) receptor (AT(2)R) provides a counter-regulatory role to AT(1)R overactivity, particularly during pathological conditions. Indeed, a potential therapeutic role for the AT(2)R is currently being promulgated with the introduction of novel AT(2)R ligands such as compound 21 (C21).
Claudia A, McCarthy, Robert E, Widdop, Kate M, Denton, Emma S, Jones   +3 more
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Angiotensin receptors in the nervous system

Brain Research Bulletin, 1998
In addition to its traditional role as a circulating hormone, angiotensin is also involved in local functions through the activity of tissue renin-angiotensin systems that occur in many organs, including the brain. In the brain, both systemic and presumptive neurally derived angiotensin and angiotensin metabolites act through specific receptors to ...
A M, Allen, I, Moeller, T A, Jenkins, J, Zhuo, G P, Aldred, S Y, Chai, F A, Mendelsohn   +6 more
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ONTOGENY OF ANGIOTENSIN II RECEPTORS

Cell Biology International, 1996
AbstractAside from the well known role of angiotensin II (Ang II) in blood pressure regulation and fluid homeostasis, accumulating evidence suggests that the octapeptide hormone also plays a role in growth and development. There are two major classes of Ang II receptors (AT1and AT2) which mediate Ang II action.
S, Shanmugam, K, Sandberg
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Human angiotensin receptor subtypes

Current Opinion in Nephrology and Hypertension, 1994
The rapid expansion of our knowledge of angiotensin receptors has been led by the development of subtype-specific angiotensin II receptor antagonists and by the cloning and sequencing of the AT1 receptor in angiotensin II. Although some actions of angiotensin II have been attributed to AT2 subtype receptors, the importance of these binding sites ...
Ronald D. Smith, &NA; Pieter, &NA; Timmermans   +2 more
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The Biology of Angiotensin II Receptors

American Journal of Kidney Diseases, 1993
Angiotensin II is very important in the regulation of blood pressure. This small peptide binds to cell surface receptors, initiating a wide diversity of physiologic responses. There are two major subtypes of angiotensin II receptors referred to as AT1 and AT2.
K E, Bernstein, B C, Berk
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Angiotensin receptor(s) in fowl

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 2001
The cloning of the avian Ang II receptor shows that it is molecularly close to the AT(1)-type mammalian receptor. However, pharmacological characterization in transfected cells shows that, even though the avian receptor is coupled to the phospholipase C, as is the AT(1), its profile of specificity towards antagonists appears different from that of the ...
Kempf, Hervé, Corvol, Pierre
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