Results 201 to 210 of about 2,530,199 (377)

The Impact of Hydrostatic Pressure on Fractional Flow Reserve in Saphenous Vein Grafts

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The relationship between height differences related to graft anatomy and physiological pressure indices in coronary bypass grafts has not been studied. We sought to study the impact of hydrostatic pressure on fractional flow reserve (FFR) in saphenous vein grafts (SVGs).
Roel Hoek, Sina Porouchani, Ruben W. de Winter, Yvemarie B. O. Somsen, Pepijn A. van Diemen, Ruurt A. Jukema, Jos W. Twisk, Adriaan Wilgenhof, Alexander W. den Hartog, Niels J. Verouden, Nils R. Planken, Ibrahim Danad, Alexander Nap, Paul Knaapen   +13 more
wiley   +1 more source

Multicenter trial of olmesartan. Main results

Терапевтический архив, 2011
Development and introduction into practice of medicines reducing activity of the renin-angiotensin-aldosteron system the key element of which is angiotensin II (ATII) resulted in a significant improvement of efficacy of cardiovascular diseases treatment.
Fail' Taipovich Ageev, Ol'ga Nikolaevna Svirida, F T Ageev, O N Svirida   +3 more
doaj  

Real Time Hemodynamic Monitoring During M‐TEER Using Electrical Cardiometry

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Mitral regurgitation is a common valvular dysfunction causing patient morbidity and mortality. Mitral transcatheter edge‐to‐edge repair (M‐TEER) allows grasping of valvular leaflets and approximation via a small implant, thus reducing mitral regurgitation (MR).
Andreas Goldschmied, Manuel Sigle, Ioannis Toskas, Monika Zdanyte, Mareike Bladt, Meinrad Gawaz, Tobias Geisler   +6 more
wiley   +1 more source

Rapid response to fast viral evolution using AlphaFold 3-assisted topological deep learning [PDF]

arXiv
The fast evolution of SARS-CoV-2 and other infectious viruses poses a grand challenge to the rapid response in terms of viral tracking, diagnostics, and design and manufacture of monoclonal antibodies (mAbs) and vaccines, which are both time-consuming and costly. This underscores the need for efficient computational approaches.
arxiv  

PCSK‐9 Inhibitors Can Significantly Improve the Coronary Slow Flow Caused by Elevated Lipoprotein (a) in ST‐Elevation Myocardial Infarction Patients With Chronic Kidney Disease

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary slow flow and no reflow significantly predict poor prognosis in acute myocardial infarction (AMI) patients, especially those with chronic kidney disease (CKD). Early identification of factors contributing to these conditions can mitigate ischemic events and improve outcomes.
Hao Xu, Ziqing Wang, Dan Chen, Haojie Zhang, Junhua Ge, Jian Li   +5 more
wiley   +1 more source

Paclitaxel‐Coated Balloons for Femoropopliteal Artery Disease Treatment in French Patients: A Longitudinal Observational Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Clinical studies have demonstrated the safety and effectiveness of drug‐coated balloon (DCB) angioplasty for femoropopliteal revascularization. Long‐term studies in routine practice are limited. Aims The aim of this study was to assess long‐term outcomes after DCB angioplasty for femoropopliteal peripheral artery disease in a real ...
Yann Gouëffic, Maxime Dubosq‐Lebaz, Jean‐François Heautot, Aurore Tricotel, Antoine Sauguet   +4 more
wiley   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review

Chronic Diseases and Translational Medicine, EarlyView.
PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi, Yunia Sribudiani, Steven Yulius Usman, Eric Ricardo Yonatan, Ahmedz Widiasta, Noormarina Indraswari, Ria Bandiara, Nanny N. M. Soetedjo   +7 more
wiley   +1 more source

Intrarenal Angiotensin III Is the Predominant Agonist for Proximal Tubule Angiotensin Type 2 Receptors

HYPERTENSION, 2012
Brandon A. Kemp, John F. Bell, Daniele M. Rottkamp, N. Howell, Weijian Shao, L. Navar, S. Padia, R. Carey   +7 more
semanticscholar   +1 more source

A Phase 1C, Open Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of DM199 Administered Intravenously with a Polyvinyl Chloride Bag in Adult Healthy Subjects and Adults Recently Taking Angiotensin‐Converting Enzyme Inhibitors

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This small phase 1C, open‐label, single ascending dose study evaluated the safety, tolerability, and pharmacokinetics (PKs) of DM199, a recombinant form of human tissue kallikrein‐1 (KLK1). A small sample size of both healthy subjects and hypertensive adults recently taking angiotensin‐converting enzyme inhibitors was studied. KLK1 has a known
Michael Giuffre, Annette D. Lista, Nick Paulson, Lorianne Masuoka   +3 more
wiley   +1 more source