Results 151 to 160 of about 1,004,480 (189)

Chimeric antigen receptor T cell therapy: Revolutionizing cancer treatment. [PDF]

open access: yesWorld J Clin Oncol
Arjumand S   +4 more
europepmc   +1 more source

In silico design and immunoinformatics assessment of a multiepitope vaccine targeting borealpox virus. [PDF]

open access: yesSci Rep
Naveed M   +9 more
europepmc   +1 more source
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Structural principles of B cell antigen receptor assembly

Nature, 2022
The B cell antigen receptor (BCR) is composed of a membrane-bound class M, D, G, E or A immunoglobulin for antigen recognition1-3 and a disulfide-linked Igα (also known as CD79A) and Igβ (also known as CD79B) heterodimer (Igα/β) that functions as the signalling entity through intracellular immunoreceptor tyrosine-based activation motifs (ITAMs)4,5. The
Ying Dong   +8 more
openaire   +3 more sources

The B-cell antigen receptor complex

Immunology Today, 1991
Abstract Here, Michael Reth, John Cambier and colleagues review the genetics, biochemistry and cell biology o f the recently-identified accessory components o f the B-cell antigen receptor.
M, Reth   +6 more
openaire   +2 more sources

B cell antigen receptor signaling 101

Molecular Immunology, 2004
All cells continually survey their environment and make decisions based on cues encountered. This requires specific receptors that detect such cues, then transduce signals that initiate the appropriate responses. B lymphocytes provide an archetypal model for such 'adaptive' cellular responses, where signals transmitted by the B cell Ag-receptor (BCR ...
Joseph M, Dal Porto   +5 more
openaire   +2 more sources

B cell antigen receptors

Current Opinion in Immunology, 1994
Antigen receptors have a dual role on the surface of B lymphocytes, namely the binding and internalization of antigens and the activation of the antigen-recognizing B cell. The structural requirements for internalization are still a matter of controversy; but as far as signalling is concerned it is becoming increasingly apparent that the antigen ...
openaire   +2 more sources

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