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Chimeric antigen receptor T cell therapy: Revolutionizing cancer treatment. [PDF]
Arjumand S +4 more
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UniTope & TraCR: A Universal Tool to Tag, Enrich, and Track TCR-T Cells and Therapeutic Proteins. [PDF]
Mishra K, Lösch B, Schendel DJ.
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In silico design and immunoinformatics assessment of a multiepitope vaccine targeting borealpox virus. [PDF]
Naveed M +9 more
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Strategies for the Development of NK Cell-Based Therapies for Cancer Treatment. [PDF]
Budagova T +3 more
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Structural principles of B cell antigen receptor assembly
Nature, 2022The B cell antigen receptor (BCR) is composed of a membrane-bound class M, D, G, E or A immunoglobulin for antigen recognition1-3 and a disulfide-linked Igα (also known as CD79A) and Igβ (also known as CD79B) heterodimer (Igα/β) that functions as the signalling entity through intracellular immunoreceptor tyrosine-based activation motifs (ITAMs)4,5. The
Ying Dong +8 more
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The B-cell antigen receptor complex
Immunology Today, 1991Abstract Here, Michael Reth, John Cambier and colleagues review the genetics, biochemistry and cell biology o f the recently-identified accessory components o f the B-cell antigen receptor.
M, Reth +6 more
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B cell antigen receptor signaling 101
Molecular Immunology, 2004All cells continually survey their environment and make decisions based on cues encountered. This requires specific receptors that detect such cues, then transduce signals that initiate the appropriate responses. B lymphocytes provide an archetypal model for such 'adaptive' cellular responses, where signals transmitted by the B cell Ag-receptor (BCR ...
Joseph M, Dal Porto +5 more
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Current Opinion in Immunology, 1994
Antigen receptors have a dual role on the surface of B lymphocytes, namely the binding and internalization of antigens and the activation of the antigen-recognizing B cell. The structural requirements for internalization are still a matter of controversy; but as far as signalling is concerned it is becoming increasingly apparent that the antigen ...
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Antigen receptors have a dual role on the surface of B lymphocytes, namely the binding and internalization of antigens and the activation of the antigen-recognizing B cell. The structural requirements for internalization are still a matter of controversy; but as far as signalling is concerned it is becoming increasingly apparent that the antigen ...
openaire +2 more sources

