Results 21 to 30 of about 26,165 (305)
Hormone-stimulated modulation of endocytic trafficking in osteoclasts [PDF]
, 2012 Copyright @ 2012 Stenbeck, Lawrence and Albert. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and ...
Stenbeck, G +11 more
core +1 more source
The Scientific World Journal, 2001 Calcitonin, CGRP, adrenomedullin, and amylin require both CRLR (calcitonin-gene receptor like receptor) and receptor activity modifying proteins (RAMP1, RAMP2, and RAMP3) in different combinations for expression of selective, functional receptors[1].
Z. Razzaque +6 more
doaj +1 more source
The Molecular Control of Calcitonin Receptor Signaling [PDF]
ACS Pharmacology & Translational Science, 2019 The calcitonin receptor (CTR) is a class B G protein-coupled receptor (GPCR) that responds to the peptide hormone calcitonin (CT). CTs are clinically approved for the treatment of bone diseases. We previously reported a 4.1 Å structure of the activated CTR bound to salmon CT (sCT) and heterotrimeric Gs protein by cryo-electron microscopy (Liang, Y.-L.,
Emma dal Maso +17 more
openaire +6 more sources
CGRP Receptor Family and Accessory Protein Localization: Implications for Predicted Function
The Scientific World Journal, 2001 Calcitonin gene-related peptide (CGRP), adrenomedullin, amylin, and calcitonin are functionally related neuropeptides. Certain of these peptides mediate their action through receptors which have common components, such as the receptor activity modifying ...
K.R. Oliver
doaj +1 more source
Molecular Metabolism, 2021 Background: Therapies for metabolic diseases are numerous, yet improving insulin sensitivity beyond that induced by weight loss remains challenging. Therefore, search continues for novel treatment candidates that can stimulate insulin sensitivity and ...
Nina Sonne +2 more
doaj +1 more source
Calcitonin receptors in GtoPdb v.2023.1
, 2023 This receptor family comprises a group of receptors for the calcitonin/CGRP family of peptides. The calcitonin (CT), amylin (AMY), calcitonin gene-related peptide (CGRP) and adrenomedullin (AM) receptors (nomenclature as agreed by the NC-IUPHAR ...
Walker, Christopher S. +7 more
core +1 more source
Calcitonin/Amylin Receptors and Ramps
The Scientific World Journal, 2001 Our understanding of G protein-coupled receptor function has recently expanded to encompass novel protein interactions that underlie both cell surface receptor expression and the exhibited phenotype. The most notable examples are those involving receptor
Patrick M. Sexton
doaj +1 more source
Salmon Calcitonin Attenuates Some Behavioural Responses to Nicotine in Male Mice
Frontiers in Pharmacology, 2021 The behavioural responses to nicotine involve appetite-regulatory hormones; however, the effects of the anorexigenic hormone amylin on reward-related behaviours induced by nicotine remain to be established.
Cajsa Aranäs +5 more
doaj +1 more source
Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes [PDF]
, 2011 Context: Increased plasma levels of glucose-dependent insulinotropic polypeptide (GIP), calcitonin CT gene-related peptide (CGRP)-I, and procalcitonin (Pro-CT) are associated with obesity.
Beat Müller +21 more
core +1 more source
Possible involvement of neuropeptide and neurotransmitter receptors in Adenomyosis
Reproductive Biology and Endocrinology, 2021 Background Accumulating data indicate that sensory nerve derived neuropeptides such as substance P and calcitonin gene related-protein (CGRP) can accelerate the progression of endometriosis via their respective receptors, so can agonists to their ...
Xiaofang Xu +3 more
doaj +1 more source