Results 211 to 220 of about 12,370,091 (268)

Neurotransmitter regulatory networks in persistent postural-perceptual dizziness: potential mechanisms and therapeutic implications. [PDF]

Front Neurol
Zhu Y, Han Q, Teng X, Jing T, Sun L.
europepmc   +1 more source

Common Mechanisms in Migraine, Migraine-Related Neck Pain, and Low Back Pain: Implications for Treatment. [PDF]

Pain Ther
Onan D, Kodounis M, Pellesi L, Waliszewska-Prosół M, Martelletti P.   +4 more
europepmc   +1 more source

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Calcitonin gene-related peptide and its receptor in the thymus

Peptides, 1995
Calcitonin gene-related peptide (CGRP), a 37-amino acid residue neuropeptide, was immunostained in rat thymus at two sites: a subpopulation of thymic epithelial cells, namely subcapsular/perivascular cells, were heavily stained besides some nerve fibers surrounding arteries and arterioles.
B, Kurz, B, von Gaudecker, A, Kranz, B, Krisch, R, Mentlein   +4 more
openaire   +2 more sources

Interaction of calcitonin-gene-related peptide with its receptors

Biochemical Society Transactions, 2002
The receptor for calcitonin-gene-related peptide (CGRP) is a heterodimer formed by calcitonin-receptor-like receptor (CRLR), a type II (family B) G-protein-coupled receptor, and receptor-activity-modifying protein 1 (RAMP1), a single-membrane-pass protein. It is likely that the first seven or so amino acids of CGRP (which form a disulphide-bonded loop)
A C, Conner, D L, Hay, S G, Howitt, K, Kilk, U, Langel, M, Wheatley, D M, Smith, D R, Poyner   +7 more
openaire   +2 more sources

Calcitonin Gene-Related Peptide: Multiple Actions, Multiple Receptors

Pharmacology & Therapeutics, 1992
Calcitonin gene-related peptide (CGRP) shows diversity both in its effects and its receptors. It is likely to have roles as a neurotransmitter, neuromodulator, local hormone and trophic factor. Its effects include rapid changes in neuronal activity, relaxation of many types of smooth muscle, actions on metabolism and changes in gene expression ...
David R Poyner
exaly   +3 more sources

Genomic and Expression Analysis of Canine Calcitonin Receptor-stimulating Peptides and Calcitonin/Calcitonin Gene-related Peptide*

The Journal of Biochemistry, 2008
Calcitonin receptor-stimulating peptides (CRSPs) are new members of the calcitonin/calcitonin gene-related peptide (CT/CGRP) family identified in pigs, dogs and other domestic animals, and CRSP-1 is an active ligand for the CT receptor (CT-R). We recently sequenced porcine CRSP genes (Crsps) and found similarity with the CT/CGRP gene (Ct/Cgrp) in ...
Tsukasa, Osaki, Takeshi, Katafuchi, Naoto, Minamino   +2 more
openaire   +2 more sources

Action of Calcitonin Gene-Related Peptide at the Calcitonin Receptor of the T47D Cell Line

Hormone and Metabolic Research, 1987
Some effects of calcitonin (CT) can also be produced by calcitonin gene-related peptide (CGRP), an alternative product of the calcitonin gene. This might be mediated by interaction of CGRP at the CT-receptor site. The human breast cancer cell line T47D possesses well characterized CT-receptors (KD = 2.3 x 10(-10) M for 125I salmon CT).
F, Raue, H G, Schneider, A, Zink, R, Ziegler   +3 more
openaire   +2 more sources

Interaction of Calcitonin and Calcitonin Gene-Related Peptide at Receptor Sites in Target Tissues

Science, 1985
Discrete receptor sites for calcitonin (CT) and calcitonin gene-related peptide (CGRP) were found in the nervous system and in peripheral tissues. Each peptide was capable of cross-reacting with the specific receptor of the other. In contrast to CT receptors, CGRP receptors were not linked to adenylate cyclase.
D, Goltzman, J, Mitchell
openaire   +2 more sources