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Chemokines and Chemokine Receptors in Scleroderma

International Archives of Allergy and Immunology, 2006
Scleroderma is a connective tissue disease with unknown etiology characterized by excessive deposition of extracellular matrix in the skin. Cellular infiltrates of certain immune cells and proinflammatory mediators are suggested to play a crucial role in cutaneous fibrosis, forming complicated networks between fibroblasts and immune cells via cell-cell
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Chemokines and Chemokine Receptors Encoded by Cytomegaloviruses

2008
CMVs carry several genes that are homologous to genes of the host organism. These include genes homologous to those encoding chemokines (CKs) and G protein-coupled receptors (GPCRs). It is generally assumed that these CMV genes were hijacked from the host genome during the long co-evolution of virus and host.
Beisser, PS +3 more
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Chemokine/Chemokine Receptor Nomenclature