Results 21 to 30 of about 22,074 (250)
Folia Histochemica et Cytobiologica, 2010 Chemokines and its receptors stimulate tumor growth, migration and invasion. In this study we evaluated the expression and function of CXCR3 and CXCR7 receptors in cervical carcinoma, rhabdomyosarcoma and glioblastoma cell lines.
Elzbieta Trzyna +3 more
doaj +3 more sources
Chemokine Receptor CXCR3 Expression in Inflammatory Bowel Disease [PDF]
Inflammatory Bowel Diseases, 2001 CD4+ T lymphocytes in the lamina propria (LP) of the gut play a central role in the immune response in inflammatory bowel disease (IBD). CXCR3 is a chemokine receptor expressed on activated T lymphocytes, and a key component for the recruitment of T helper (Th1) effector cells to the site of inflammation.
Yuan, Y.H. +5 more
openaire +5 more sources
Signal Transduction by the Chemokine Receptor CXCR3 [PDF]
Journal of Biological Chemistry, 2001 n ...
Bonacchi, Andrea +11 more
openaire +1 more source
Microorganisms, 2021 The obligate intracellular parasite Toxoplasma gondii infects warm-blooded animals, including humans. We previously revealed through a whole-brain transcriptome analysis that infection with T.
Kousuke Umeda +8 more
doaj +1 more source
Investigation into imbalance of Th1/Th2 cells in cirrhotic, hypersplenic rats
Journal of International Medical Research, 2020 Objectives To evaluate the Th1/Th2 cell profile in spleens of cirrhotic and hypersplenic rats by investigating the expression of Th1-associated chemokine receptors CXCR3, CCR5 and Th2-associated chemokine receptor CCR3.
Yunfu Lv +4 more
doaj +1 more source
Requirement of the Chemokine Receptor CXCR3 for Acute Allograft Rejection [PDF]
The Journal of Experimental Medicine, 2000 Chemokines provide signals for activation and recruitment of effector cells into sites of inflammation, acting via specific G protein–coupled receptors. However, in vitro data demonstrating the presence of multiple ligands for a given chemokine receptor, and often multiple receptors for a given chemokine, have led to concerns of biologic redundancy ...
W W, Hancock +9 more
openaire +2 more sources
Receptor Endocytosis as a Mechanism of Biased Agonism at CXCR3
The FASEB Journal, 2021 G Protein Coupled Receptors (GPCRs) are the largest class of receptors in the human genome. They are expressed in virtually every cell type and are implicated in numerous physiological processes. GPCR signaling is highly specific due to biased agonism, in which different ligands, receptors, or cellular systems selectively activate different signaling ...
Noelia Boldizsar +4 more
openaire +1 more source
CXCL9, CXCL10, CXCL11, and their receptor (CXCR3) in neuroinflammation and neurodegeneration [PDF]
Advances in Clinical and Experimental Medicine, 2018 The aim of this review is to present data from the available literature concerning CXCL9, CXCL10 and CXCL11, as well as their receptor 3 (CXCR3) in selected diseases of the central nervous system (CNS), such as tickborne encephalitis (TBE), neuroborreliosis (NB), Alzheimer's disease (AD), and multiple sclerosis (MS).
Olga M, Koper +3 more
openaire +2 more sources
CXCL9-11 chemokines and CXCR3 receptor in teleost fish species
Fish and Shellfish Immunology Reports, 2022 The coordinated migration of immune cells from lymphoid organs to in or out of the bloodstream, and towards the site of infection or tissue damage is fundamental for an efficient innate and adaptive immune response. Interestingly, an essential part of this movement is mediated by chemoattractant cytokines called chemokines.
Natalia Valdés +4 more
openaire +4 more sources
Frontline Science: Antagonism between regular and atypical Cxcr3 receptors regulates macrophage migration during infection and injury in zebrafish. [PDF]
, 2019 The CXCR3-CXCL11 chemokine-signaling axis plays an essential role in infection and inflammation by orchestrating leukocyte trafficking in human and animal models, including zebrafish.
Lombardi, Amber +11 more
core +1 more source