Results 31 to 40 of about 371,200 (274)
High expression of antioxidant proteins in dendritic cells: possible implications in atherosclerosis [PDF]
Mol Cell Proteomics 5 (04/2006) 726-36, 2006 Dendritic cells (DCs) display the unique ability to activate naive T cells and to initiate primary T cell responses revealed in DC-T cell alloreactions. DCs frequently operate under stress conditions. Oxidative stress enhances the production of inflammatory cytokines by DCs.
arxiv +1 more source
Cytokines as cellular communicators
Mediators of Inflammation, 1996 Cytokines and their receptors are involved in the pathophysiology of many diseases. Here we present a detailed review on cytokines, receptors and signalling routes, and show that one important lesson from cytokine biology is the complex and diverse ...
R. Debets, H. F. J. Savelkoul
doaj +1 more source
F1000Research, 2018 Poxviruses encode a set of secreted proteins that bind cytokines and chemokines as a strategy to modulate host defense mechanisms. These viral proteins mimic the activity of host cytokine decoy receptors but have unique properties that may enhance their ...
Bruno Hernaez, Antonio Alcami
doaj +1 more source
Single-chain tandem macrocyclic peptides as a scaffold for growth factor and cytokine mimetics
Communications Biology, 2022 Peptides composed of two or more tandemly linked macrocyclic peptides binding to growth factor/cytokine receptors (STaMPtides) are useful growth factor/cytokine mimetics.
Kenichiro Ito +8 more
doaj +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Медицинская иммунология, 2014 . Placental cell populations produce a great variety of angiogenic factors and cytokines than control angiogenesis in placenta. Functional regulation of endothelial cells proceeds via modulation of endothelial cell receptors for endogenous angiogenic and
O. I. Stepanova +5 more
doaj +1 more source
Biosensing Cytokine IL-6: A Comparative Analysis of Natural and Synthetic Receptors
Biosensors, 2020 Cytokines are a family of proteins which play a major role in the regulation of the immune system and the development of several diseases, from rheumatoid arthritis to cancer and, more recently, COVID-19.
Eleonora Alfinito +2 more
doaj +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Virus encoded cytokines and cytokine receptors
Parasitology, 1997 In order to replicate efficiently within the host, viruses have evolved multiple strategies to evade the host's immune system. In many cases viruses have actually hijacked various components of the host's immune system to ensure their own survival. One such strategy is the expression of virus encoded cytokines and cytokine receptors. Members of
G. McFADDEN, M. Barry
openaire +3 more sources