Results 11 to 20 of about 142,564 (264)

Role of Basic Fibroblast Growth Factor in Cancer: Biological Activity, Targeted Therapies, and Prognostic Value

open access: yesCells, 2023
Cancer is the leading cause of death worldwide; thus, it is necessary to find successful strategies. Several growth factors, such as vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF, FGF2), and transforming growth factor ...
Alessio Ardizzone   +10 more
doaj   +1 more source

Progress in Research on the Role of FGF in the Formation and Treatment of Corneal Neovascularization

open access: yesFrontiers in Pharmacology, 2020
Corneal neovascularization (CNV) is a sight-threatening disease usually associated with inflammatory, infectious, degenerative, and traumatic disorders of the ocular surface.
Mengji Chen   +4 more
doaj   +1 more source

Research progress of fibroblast growth factor homologous factor 1 in the pathogenesis of arrhythmia [PDF]

open access: yesJichu yixue yu linchuang, 2020
Fibroblast growth factor homologous factor 1 (FHF1) is an intracellular signaling protein, a non-specific fibroblast growth factor that does not bind to fibroblast growth factor receptors. FHF1 combines with the C-terminus of cardiac voltage-gated sodium
QIN Tao, LI Qing, LI Ju-xiang
doaj  

Expression of fibroblast growth factor receptor and its role in regulating osteoblast differentiation

open access: yesDi-san junyi daxue xuebao, 2019
Objective To investigate the changes in the expression of fibroblast growth factor receptors 1-3 (FGFR1-3) at different stages of osteogenic differentiation and clarify the role of FGFR signaling in osteogenic differentiation.
MO Qifei, YANG Peng, SU Nan, CHEN Lin
doaj   +1 more source

The Role of Fibroblast Growth Factor Receptors Inhibitors in Bladder Cancer [PDF]

open access: yesJournal of Urologic Oncology
Dysregulation of fibroblast growth factor (FGF)-receptor (FGFR) signaling, which is implicated in various oncogenic processes, including tumor proliferation, survival, migration, invasion, and angiogenesis, has been identified as a critical factor in ...
Ho Kyung Seo   +3 more
doaj   +1 more source

Microvascularization and Expression of Fibroblast Growth Factor and Vascular Endothelial Growth Factor and Their Receptors in the Mare Oviduct

open access: yesAnimals, 2021
The oviduct presents the ideal conditions for fertilization and early embryonic development. In this study, (i) vascularization pattern; (ii) microvascular density; (iii) transcripts of angiogenic factors (FGF1, FGF2, VEGF) and their receptors—FGFR1 ...
Pedro Pinto-Bravo   +10 more
doaj   +1 more source

FGFR1 (Fibroblast Growth Factor Receptor 1) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on FGFR1 (fibroblast growth factor receptor 1), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +5 more sources

Fibroblast Growth Factor Receptors (FGFRs): Structures and Small Molecule Inhibitors

open access: yesCells, 2019
Fibroblast growth factor receptors (FGFRs) are a family of receptor tyrosine kinases expressed on the cell membrane that play crucial roles in both developmental and adult cells.
Shuyan Dai   +4 more
doaj   +1 more source

Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A). [PDF]

open access: yesPLoS Pathogens, 2013
Botulinum neurotoxin serotype A (BoNT/A) causes transient muscle paralysis by entering motor nerve terminals (MNTs) where it cleaves the SNARE protein Synaptosomal-associated protein 25 (SNAP25206) to yield SNAP25197.
Birgitte P S Jacky   +12 more
doaj   +1 more source

Cross-Talk between Fibroblast Growth Factor Receptors and Other Cell Surface Proteins

open access: yesCells, 2019
Fibroblast growth factors (FGFs) and their receptors (FGFRs) constitute signaling circuits that transmit signals across the plasma membrane, regulating pivotal cellular processes like differentiation, migration, proliferation, and apoptosis.
Marta Latko   +6 more
doaj   +1 more source

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