Results 11 to 20 of about 479,694 (316)

G-Protein-Coupled Receptors

British Journal of Pharmacology, 2011
Receptors coupled to heterotrimeric guanine nucleotide-binding proteins, the socalled G-protein-coupled receptors (GPCR), represent the largest set of plasmalemmal ...
S P H Alexander, John A. Peters, Alistair Mathie   +2 more
openaire   +5 more sources

Atropine-functionalized gold nanoparticles binding to muscarinic receptors after passage across the intestinal epithelium

Royal Society Open Science, 2022
Gold nanoparticles have a high potential to be a treatment of diseases by their specific drug delivery properties and multivalent receptor stimulation.
Rebecca Claßen, Ervice Pouokam, Matthias Wickleder, Martin Diener, Annabelle Mattern   +4 more
doaj   +1 more source

G-protein-coupled receptors at a glance [PDF]

Journal of Cell Science, 2003
[No abstract available]
Douglas J. Sheffler, Bryan L. Roth, Wesley K. Kroeze   +2 more
openaire   +3 more sources

G Protein-Coupled Receptors in Cancer [PDF]

International Journal of Molecular Sciences, 2016
Despite the fact that G protein-coupled receptors (GPCRs) are the largest signal-conveying receptor family and mediate many physiological processes, their role in tumor biology is underappreciated. Numerous lines of evidence now associate GPCRs and their downstream signaling targets in cancer growth and development.
Beatrice Uziely, Arun Kancharla, Myriam Maoz, Rachel Bar-Shavit, Sorina Grisaru-Granovsky, Daniel Agranovich, Jeetendra Kumar Nag   +6 more
openaire   +3 more sources

Constitutive Activity among Orphan Class-A G Protein Coupled Receptors. [PDF]

PLoS ONE, 2015
The purpose of this study was to evaluate the extent of constitutive activity among orphan class-A G protein coupled receptors within the cAMP signaling pathway.
Adam L Martin, Michael A Steurer, Robert S Aronstam   +2 more
doaj   +1 more source

Revising Berg-Purcell for finite receptor kinetics [PDF]

, 2021
From nutrient uptake, to chemoreception, to synaptic transmission, many systems in cell biology depend on molecules diffusing and binding to membrane receptors. Mathematical analysis of such systems often neglects the fact that receptors process molecules at finite kinetic rates.
arxiv   +1 more source

Olfactory receptors: G protein‐coupled receptors and beyond

Journal of Neurochemistry, 2009
Sensing the chemical environment is critical for all organisms. Diverse animals from insects to mammals utilize highly organized olfactory system to detect, encode, and process chemostimuli that may carry important information critical for health ...
M. Spehr, S. Munger
semanticscholar   +1 more source

Evolution of vertebrate GnRH receptors from the perspective of a basal vertebrate

Frontiers in Endocrinology, 2012
This minireview provides the current status on gonadotropin-releasing hormone receptors (GnRH-R) in vertebrates, from the perspective of a basal vertebrate, the sea lamprey, and provides an evolutionary scheme based on the recent advance of whole genome ...
Stacia A Sower, Wayne A Decatur, Nerine T Joseph, Mihael eFreamat   +3 more
doaj   +1 more source

G Protein-Coupled Receptors: Undervalued Targets for Cancer Therapy

Iraqi Journal of Pharmaceutical Sciences, 2022
Despite the G protein-coupled receptors (GPCRs) being the largest family of signalling proteins at the surface of cells, their potential to be targeted in cancer therapy is still under-utilised.
Ismail Ibrahim Al-Janabi
doaj   +1 more source

Neuropeptide G Protein-Coupled Receptors as Oncotargets

Frontiers in Endocrinology, 2018
Neuropeptide G protein-coupled receptors (GPCRs) are overexpressed on numerous cancer cells. In a number of tumors, such as small cell lung cancer (SCLC), bombesin (BB) like peptides and neurotensin (NTS) function as autocrine growth factors whereby they
Terry W. Moody, Irene Ramos-Alvarez, Robert T. Jensen   +2 more
doaj   +1 more source