Results 211 to 220 of about 301,762 (292)

Memantine inhibits calcium-permeable AMPA receptors. [PDF]

Nat Commun
Carrillo E, Montaño Romero A, Gonzalez CU, Turcu AL, Vázquez S, Twomey EC, Jayaraman V.   +6 more
europepmc   +1 more source

Targeted Proteomics upon Treatment with Tofersen Identifies Novel Response Markers for Superoxide Dismutase 1‐Linked Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Tofersen is the first effective and approved therapy for superoxide dismutase 1 (SOD1)‐associated amyotrophic lateral sclerosis (ALS [SOD1‐ALS]). Following treatment with tofersen, neurofilament levels in patients' cerebrospinal fluid (CSF) and serum seem to respond earlier than clinical parameters.
Christina Steffke, Karthik Baskar, Franziska Bachhuber, Maximilian Wiesenfarth, Johannes Dorst, Joachim Schuster, Florian Schöberl, Peter Reilich, Martin Regensburger, Alexander German, René Günther, Maximilian Vidovic, Susanne Petri, Thomas Meyer, Tim Hagenacker, Julian Grosskreutz, Ute Weyen, Patrick Weydt, Thomas Haarmeier, Paul Lingor, Joachim Wolf, Andreas Hermann, Johannes Prudlo, Kornelia Günther, Antje Knehr, Zeynep Elmas, Zeljko Uzelac, Simon Witzel, Wolfgang Philipp Ruf, Axel Freischmidt, Ritchie Ho, Albert C. Ludolph, Jochen H. Weishaupt, Hayrettin Tumani, Patrick Oeckl, David Brenner, Alberto Catanese   +36 more
wiley   +1 more source

Approaches to Enhance Photodynamic Therapy of Lung Cancer: Potential Application of Nanoparticles

Advanced NanoBiomed Research, EarlyView.
Bioactive ligand‐targeted nanocarriers can accommodate functionalization with numerous targeting ligands for effective delivery of photosensitizers (PSs) within targeted photodynamic therapy. Various targeting moieties including peptides, antibodies, carbohydrates, aptamers, proteins, and PS anticancer molecules can be attached to nanomaterials.
Nokuphila Winifred Nompumelelo Simelane, Heidi Abrahamse   +1 more
wiley   +1 more source

Does Dysregulation Of The Indirect Pathway Contribute To The Pathophysiology Of Catatonia Through Neurotransmitter Imbalance? [PDF]

Clin Neuropsychiatry
Seif P.
europepmc   +1 more source

Innovative Therapeutic Strategies Targeting the Network Architecture of Glioblastoma. [PDF]

Clin Cancer Res
Beichert J, Hoffmann DC, Winkler F, Ratliff M.   +3 more
europepmc   +1 more source

Long-Term Exposure to 6-PPD Quinone Inhibits Glutamate Synthesis and Glutamate Receptor Function Associated with Its Toxicity Induction in <i>Caenorhabditis elegans</i>. [PDF]

Toxics
Wang W, Li Y, Wang D.
europepmc   +1 more source

The Role of GPR120 on the Fatty Orosensation in Humans and Sensory Characteristics of GPR120 Agonists in Low‐Fat Oil‐In Water (O/W) Emulsified Foods

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT The addition of GPR120 agonists to vegetable oil or a fat‐containing food system enhances the fatty orosensation, an oily mouth‐coating sensed 5–10 s after tasting, in humans, although they have no fatty orosensation by themselves. To elucidate the role of GPR120 in the fatty orosensation in humans, the effects of GPR120 agonists and an ...
Naoya Iwasaki, Seiji Kitajima, Kazuhiro Sakamoto, Motonaka Kuroda   +3 more
wiley   +1 more source

Central Neurophysiological Alterations in Dystrophic mdx Mice Correlate With Reduced Hippocampal Levels of the Endogenous NMDA Receptor Ligand D-Aspartate. [PDF]

J Neurochem
Mastrostefano F, Garofalo M, Nuzzo T, Bruno C, Errico F, Usiello A, De Stefano ME.   +6 more
europepmc   +1 more source