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Chapter 24 Glutamate receptors in epilepsy
1998Glutamatergic synapses play a critical role in all epileptic phenomena. Broadly enhanced activation of post-synaptic glutamate receptors (ionotropic and metabotropic) is proconvulsant. Antagonists of NMDA receptors and AMPA receptors are powerful anticonvulsants in many animal models of epilepsy.
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Metabotropic glutamate receptors
Pharmacology Biochemistry and Behavior, 2002openaire +3 more sources
Ischemia-Triggered Glutamate Excitotoxicity From the Perspective of Glial Cells
Frontiers in Cellular Neuroscience, 2020Jan Kriska, Miroslava Anderova
exaly
2000
During the past decade, pharmacological, electrophysiological, and molecular biological studies have yielded a detailed, albeit imperfect picture of the assembly and operation of NMDA receptors in the central nervous system. While a review of all aspects of NMDA receptor biology is clearly beyond the scope of this chapter, it is important to review ...
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During the past decade, pharmacological, electrophysiological, and molecular biological studies have yielded a detailed, albeit imperfect picture of the assembly and operation of NMDA receptors in the central nervous system. While a review of all aspects of NMDA receptor biology is clearly beyond the scope of this chapter, it is important to review ...
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1994
Publisher Summary This chapter focuses on the insect glutamate receptors (GluR). Glutamate receptors (GluR) of vertebrate CNS have been cloned and these membrane macromolecules have been implicated in important functions, such as information storage, and in a number of disorders of human brain, including cerebral ischaemia.
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Publisher Summary This chapter focuses on the insect glutamate receptors (GluR). Glutamate receptors (GluR) of vertebrate CNS have been cloned and these membrane macromolecules have been implicated in important functions, such as information storage, and in a number of disorders of human brain, including cerebral ischaemia.
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Targeting glutamate signalling in depression: progress and prospects
Nature Reviews Drug Discovery, 2017James W Murrough +2 more
exaly
Role of glutamate metabolism in bacterial responses towards acid and other stresses
Journal of Applied Microbiology, 2013Conor Feehily, Kimon Andreas Karatzas
exaly