Results 11 to 20 of about 51,381 (211)
Transcriptional Mechanisms Underlying Sensitization of Peripheral Sensory Neurons by Granulocyte-/Granulocyte-Macrophage Colony Stimulating Factors [PDF]
Background Cancer-associated pain is a major cause of poor quality of life in cancer patients and is frequently resistant to conventional therapy. Recent studies indicate that some hematopoietic growth factors, namely granulocyte macrophage colony ...
Kiran Kumar Bali +5 more
doaj +2 more sources
Natural killer cells (NK cells) are a population of innate immune lymphocytes capable of cytolysis of infected or transformed cells without prior sensitization.
A. A. Davydova +8 more
doaj +3 more sources
Granulocyte colony-stimulating factor and leukemogenesis [PDF]
THE granulocyte colony-stimulating factor (G-CSF) plays an important role in normal granulopoiesis. Its functions are mediated by specific receptors on the surface of responsive cells and, upon ligand binding, several cytoplasmic tyrosine kinases are ...
Lorena Lobo de Figueiredo +2 more
doaj +2 more sources
Defining Genome-Wide Expression and Phenotypic Contextual Cues in Macrophages Generated by Granulocyte/Macrophage Colony-Stimulating Factor, Macrophage Colony-Stimulating Factor, and Heat-Killed Mycobacteria [PDF]
Heat-killed (HK) Mycobacterium obuense (NCTC13365) is currently being evaluated in the clinic as an immunotherapeutic agent for cancer treatment. Yet, the molecular underpinnings underlying immunomodulatory properties of HK M.
Samer Bazzi +9 more
doaj +2 more sources
Growing evidence shows that granulocyte macrophage colony-stimulating factor (GM-CSF) has progression-promoting potentials in certain solid tumors, which is largely attributed to the immunomodulatory function of this cytokine in tumor niches.
Yaqiong Chen +14 more
doaj +2 more sources
Modeling the Hematopoietic Landscape
Some time ago, we proposed a continuum-like view of the lineages open to hematopoietic stem cells (HSCs); each HSC self-renews or chooses from the spectrum of all end-cell options and can then “merely” differentiate.
Geoffrey Brown, Rhodri Ceredig
doaj +1 more source
The effects of hematopoietic growth factors on neurite outgrowth. [PDF]
Stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF) are initially discovered as the essential hematopoietic growth factors regulating bone marrow stem cell proliferation and differentiation, and SCF in combination with G-CSF (SCF+G ...
Ye Su +4 more
doaj +1 more source
The correlation among olfactory dysfunction, spinal cord injury (SCI), subjective cognitive decline, and neurodegenerative dementia has been established. Impaired olfaction is considered a marker for neurodegeneration.
Muh-Shi Lin +5 more
doaj +1 more source
Genetic Predisposition and Inflammatory Inhibitors in COVID-19: Where Do We Stand?
Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and the resulting coronavirus disease-19 (COVID-19) have led to a global pandemic associated with high fatality rates.
Marios Sagris +5 more
doaj +1 more source
Clinical biological and genetic heterogeneity of the inborn errors of pulmonary surfactant metabolism [PDF]
Pulmonary surfactant is a multimolecular complex located at the air-water interface within the alveolus to which a range of physical (surface-active properties) and immune functions has been assigned. This complex consists of a surface-active lipid layer
Griese, Matthias +5 more
core +1 more source

