Results 31 to 40 of about 51,381 (211)

Role of Lipid Rafts in Hematopoietic Stem Cells Homing, Mobilization, Hibernation, and Differentiation

open access: yesCells, 2019
Hematopoietic stem cells (HSCs) are multipotent, self-renewing cells that can differentiate into myeloid or lymphoid cells. The mobilization and differentiation processes are affected by the external environment, such as extracellular matrix and soluble ...
Munther Alomari   +5 more
doaj   +1 more source

IL-5 and GM-CSF, but Not IL-3, Promote the Proliferative Properties of Inflammatory-like and Lung Resident-like Eosinophils in the Blood of Asthma Patients

open access: yesCells, 2022
Blood eosinophils can be described as inflammatory-like (iEOS-like) and lung-resident-like (rEOS-like) eosinophils. This study is based on the hypothesis that eosinophilopoetins such as interleukin (IL)-3 and IL-5 and granulocyte-macrophage colony ...
Jolita Palacionyte   +6 more
doaj   +1 more source

Expression of granulocyte colony-stimulating factor receptor in rectal cancer

open access: yesWorld Journal of Gastroenterology, 2014
To evaluate whether granulocyte colony-stimulating factor receptor (G-CSFR) expression before preoperative irradiation can predict the radiosensitivity of rectal cancer.The expression of G-CSFR was examined, using immunohistochemistry, in biopsy specimens from 126 patients with locally advanced rectal adenocarcinoma before preoperative irradiation ...
Xiao-Dong, Yang   +3 more
openaire   +2 more sources

Characterization of granulocyte colony‐stimulating factor receptor expressed on human lymphocytes [PDF]

open access: yesBritish Journal of Haematology, 2002
Summary. We have studied the characterization of granulocyte colony‐stimulating factor receptor (G‐CSFR) in human lymphocytes. About one‐third to one‐quarter of the B lymphocytes from peripheral B‐cell sources displayed G‐CSF binding on the two‐colour immunofluorescence study.
Keiko, Morikawa   +3 more
openaire   +2 more sources

Cloning and Expression of Bioactive Human Granulocyte Colony Stimulating Factor in Pichia pastoris

open access: yes, 2010
For over ten years, recombinant human Granulocyte Colony Stimulating Factor (hG-CSF) has been broadly used in clinical applications. Many sources of G-CSF have the disadvantage of being in intracellular or aggregated form.
簡素芳; Chien, Su-Fang   +1 more
core   +1 more source

Rhinovirus and airway allergy

open access: yesAllergology International, 2004
Rhinoviruses cause the majority of common colds, which often provoke wheezing in patients with asthma. The precise mechanisms responsible for the rhinovirus infection-induced exacerbations of bronchial asthma remain uncertain.
Mutsuo Yamaya, Hidetada Sasaki
doaj   +1 more source

Successful Treatment of Pediatric Refractory/Relapsed AML with KIR-Ligand-Mismatched Cord Blood Transplant after FLAG-IDA Reinduction Therapy with or without the GO Regimen

open access: yesCase Reports in Hematology, 2020
Prognosis in pediatric patients with refractory/relapsed acute myeloid leukemia (AML) is grim, and there is no standard treatment for such patients. Combined treatment with intensive chemotherapy and gemtuzumab ozogamicin (GO), a monoclonal anti-CD33 ...
Daisuke Toyama   +9 more
doaj   +1 more source

Activation Mechanism of Granulocyte Colony-Stimulating Factor Receptor

open access: yesNihon Kessho Gakkaishi, 2006
The crystal structure of the signaling complex of human granulocyte colony-stimulating factor (GCSF) and ligand binding region of human GCSF receptor (GCSF-R) has been determined to 2.8 A resolution. The GCSF : GCSF-R complex formed a 2 : 2 stoichiometry via a crossover interaction between the Ig-like domains of GCSF-R and GCSF. The conformation of the
TAMADA, Taro   +2 more
openaire   +2 more sources

Granulocyte colony-stimulating factor and its receptor in acute promyelocytic leukemia [PDF]

open access: yesAmerican Journal of Hematology, 1998
Expression of granulocyte colony-stimulating factor (G-CSF) receptor (G-CSFR) and in vitro proliferative response to G-CSF were investigated by quantitative immunofluorescence and [3H] thymidine uptake, respectively, in a series of acute myeloid leukemias (AML).
N, Katayama   +11 more
openaire   +2 more sources

G protein coupled receptor transcripts in human immune cells and platelets

open access: yesScientific Data
G-protein coupled receptors (GPCRs) are encoded by nonabundant mRNAs, and it is difficult to detect them reliably with the highly parallel methods that are in general use.
Arne Hansen   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy