Results 41 to 50 of about 42,332 (197)

The Immunological Correlation With Adenoid Hypertrophy and Allergic Rhinitis in Children

iNew Medicine, EarlyView.
The imbalance of Th1/Th2 and Th17/Treg cells in allergen and inflammatory responses might be associated with the development of adenoid hypertrophy, suggesting that allergic rhinitis maybe the risk factor of AH and providing a potential alternative explanation for adenoid hypertrophy pathogenesis.
Yang Song, Chao Zhang, Jun Song, Jian‐Ming Yang, Wei Wei   +4 more
wiley   +1 more source

Central Effect of Exogenous Histamine on Pain Induced by Sub-Plantar Injection of Formalin in Rabbits [PDF]

Veterinary Research Forum, 2010
In the present study, the effects of intracerebroventricular (ICV) administration of normal saline (control), histamine, mepyramine (a histamine H1-receptor antagonist) and ranitidine (a histamine H2-receptor antagonist) were investigated on the formalin-
Esmaeal Tamaddonfard
doaj  

Utilization of Knockout Mice to Examine the Potential Role of Gastric Histamine H2-Receptors in Menetrier’s Disease

Journal of Pharmacological Sciences, 2003
Menetrier’s disease is characterized by giant gastric folds with foveolar hyperplasia and cystic dilatation, hypoproteinemia, and enhanced mucus secretion. The etiology remains unresolved and an effective treatment has yet to be established. Here we show
Toshiki Ogawa, Kazuhiko Maeda, Shunsuke Tonai, Takashi Kobayashi, Takeshi Watanabe, Susumu Okabe   +5 more
doaj   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, EarlyView.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source

Basophil Activation Test as Biomarker of Severity and Threshold of Allergic Reactions to Cow's Milk During Oral Food Challenges

Allergy, EarlyView.
The threshold of reactivity during fresh milk challenges was 70% lower than that of baked milk challenges, reflecting the higher allergenicity of fresh milk. BAT was the only biomarker statistically significantly different between severity and threshold groups, for baked milk and fresh milk allergies, respectively.
Holly Boyd, Irene Bartha, Ru‐Xin Foong, Marta Krawiec, Andreina Marques‐Mejias, Hannah F. Marshall, Suzana Radulovic, Faye Harrison, Grammatiki Antoneria, Zainab Jama, Matthew Kwok, Ewa Pietraszewicz, Malak Eghleilib, Cristian Ricci, Tom Marrs, Gideon Lack, George Du Toit, Alexandra F. Santos   +17 more
wiley   +1 more source

Role of the Histaminergic System in the Inhibitory Effect of Melatonin on Broiler Chicken Feed Intake [PDF]

Poultry Science Journal
Prior investigations have postulated that melatonin, a prominent hormone produced by the pineal gland, can reduce animal food consumption. This study was designed to evaluate the involvement of central histamine H1 and H2 receptors in regulating ...
Majid Taati, Hassan Norouzian, Vahid Farhadi   +2 more
doaj   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Enhanced histamine H2 excitation of striatal cholinergic interneurons in l-DOPA-induced dyskinesia

Neurobiology of Disease, 2015
Levodopa is the most effective therapy for the motor deficits of Parkinson's disease (PD), but long term treatment leads to the development of l-DOPA-induced dyskinesia (LID).
Sean Austin O. Lim, Rong Xia, Yunmin Ding, Lisa Won, William J. Ray, Stephen A. Hitchcock, Daniel S. McGehee, Un Jung Kang   +7 more
doaj   +1 more source

Mast cells are critical for protection against peptic ulcers induced by the NSAID piroxicam. [PDF]

PLoS ONE, 2011
Many commonly used non-steroidal anti-inflammatory drugs (NSAIDs) also cause gastrointestinal toxicity, including the development of life-threatening peptic ulcers. We report that mast cell-deficient mice have an extremely high incidence of severe peptic
Daniel D Hampton, Laura P Hale
doaj   +1 more source

Selective histamine H2 receptor agonists alleviate blood-brain barrier disruption by promoting the expression of vascular protective factors following traumatic brain injury in mice

Journal of Pharmacological Sciences, 2022
Histamine is a major neurotransmitter and alleviates neuronal damage after ischemic injury via H2 receptors. Herein, we investigated the effects of H2 receptor agonists on the blood-brain barrier (BBB) disruption after traumatic brain injury (TBI).
Shotaro Michinaga, Kiyomi Sonoda, Naoki Inazuki, Manae Ezaki, Hiroki Awane, Kahori Shimizu, Shigeru Hishinuma, Hiroyuki Mizuguchi   +7 more
doaj   +1 more source