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Fc receptors for immunoglobulins and their appearance during vertebrate evolution. [PDF]
PLoS ONE, 2014 Receptors interacting with the constant domain of immunoglobulins (Igs) have a number of important functions in vertebrates. They facilitate phagocytosis by opsonization, are key components in antibody-dependent cellular cytotoxicity as well as ...
Srinivas Akula +2 more
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IgG binding characteristics of ferret Fcγ receptors [PDF]
mAbsStudies in animal models are essential to expanding the scope of interventions evaluated for safety, immunogenicity, and efficacy in clinical trials.
Xiaoxuan Ge +8 more
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IgG and Fcγ Receptors in Intestinal Immunity and Inflammation
Frontiers in Immunology, 2019 Fcγ receptors (FcγR) are cell surface glycoproteins that mediate cellular effector functions of immunoglobulin G (IgG) antibodies. Genetic variation in FcγR genes can influence susceptibility to a variety of antibody-mediated autoimmune and inflammatory ...
Tomas Castro-Dopico +3 more
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Cell Reports, 2015 Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody ...
Daniela Kao +8 more
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The Ligands for Human IgG and Their Effector Functions
Antibodies, 2019 Activation of the humoral immune system is initiated when antibodies recognize an antigen and trigger effector functions through the interaction with Fc engaging molecules.
Steven W. de Taeye +2 more
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How to select IgG subclasses in developing anti-tumor therapeutic antibodies
Journal of Hematology & Oncology, 2020 The intact antibody of human immunoglobulin (IgG) is composed of the fragment for antigen binding (Fab) and the crystallizable fragment (Fc) for binding of Fcγ receptors.
Jifeng Yu, Yongping Song, Wenzhi Tian
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Expression, Role, and Regulation of Neutrophil Fcγ Receptors
Frontiers in Immunology, 2019 Neutrophils are best known for their critical role in host defense, for which they utilize multiple innate immune mechanisms, including microbe-associated pattern recognition, phagocytosis, production of reactive oxygen species, and the release of potent
Yu Wang, Yu Wang, Friederike Jönsson
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Fcγ receptors on aging neutrophils [PDF]
Journal of Applied Oral Science, 2021 Objective Neutrophils are key effector cells of the innate immune system. They recognize antigens through membrane receptors, which are expressed during their maturation and activation. Neutrophils express FcγRII (CD32), FcγRIII (CD16), and FcγRI (CD64)
Thaís Helena GASPAROTO +8 more
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Zhongguo shuxue zazhi, 2023 Objective To investigate the effect of immunoglobulin G (IgG) dimer concentration of intravenous immunoglobulin (IVIG) on the binding ability of IgG Fc fragment to THP-1 cell surface receptors.
Tingting LEI +5 more
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The role of allergen‐specific IgE, IgG and IgA in allergic disease
Allergy. European Journal of Allergy and Clinical Immunology, 2021 Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease affecting more than 30% of the population. Exposure to even minute quantities of allergens can lead to the production of IgE antibodies in atopic individuals.
M. Shamji +6 more
semanticscholar +1 more source