Results 101 to 110 of about 44,977 (226)
Frontiers in Synaptic Neuroscience, 2018 Dopamine receptors and related signaling pathways have long been implicated in pathophysiology and treatment of mental illnesses, including schizophrenia and bipolar disorder.
Jivan Khlghatyan +3 more
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Molecular Ecology Resources, Volume 26, Issue 4, May 2026.ABSTRACT Spiders are renowned for their ecological versatility and silk‐based innovations in materials science, yet marine environments remain virtually uncolonized by this predominantly terrestrial lineage. A striking exception is the obligate intertidal spider genus Desis, whose members have evolved extraordinary physiological and behavioural ...
Fan Li +11 more
wiley +1 more source
The glutamatergic system in primary somatosensory neurons and its involvement in sensory input-dependent plasticity [PDF]
, 2018 Glutamate is the most common neurotransmitter in both the central and the peripheral nervous system. Glutamate is present in all types of neurons in sensory ganglia, and is released not only from their peripheral and central axon terminals but also from ...
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Aging Cell, Volume 25, Issue 5, May 2026.The steroid hormone ADIOL emerges as a key mediator of fasting–and caloric restriction–induced healthspan benefits in C. elegans. These regimens activate ADIOL production, which acts through the estrogen receptor β homolog NHR‐91 to reduce neural kynurenic acid levels and enhance healthspan independently of lifespan. ADIOL supplementation, even late in
Ana Guijarro‐Hernández +6 more
wiley +1 more source
Scientific ReportsZn2+ is essential for neuronal signaling, but imbalance cause cell death and neurodegenerative disorders. While the buffering system maintains low cytosolic Zn2+ concentration ([Zn2+]i), the details on physiological stimuli elevating [Zn2+]i for neuronal
Hui-Chiun Tseng +2 more
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Journal of Biomedical Science, 2010 Although taurine and glutamate are the most abundant amino acids conducting neural signals in the central nervous system, the communication between these two neurotransmitters is largely unknown.
Bulley Simon, Shen Wen
doaj +1 more source
The DLGAP family: neuronal expression, function and role in brain disorders
Molecular Brain, 2017 The neurotransmitter glutamate facilitates neuronal signalling at excitatory synapses. Glutamate is released from the presynaptic membrane into the synaptic cleft.
Andreas H. Rasmussen +2 more
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AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders
Nature Communications, 2019 Genetic variants in ionotropic glutamate receptors have been implicated in neurodevelopmental disorders. Here, the authors report heterozygous de novo mutations in the GRIA2 gene in 28 individuals with intellectual disability and neurodevelopmental ...
Vincenzo Salpietro +92 more
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THE CONCISE GUIDE TO PHARMACOLOGY 2017/18:Ligand-gated ion channels [PDF]
, 2017 The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
, +10 more
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IgG Isolated from LP-BM5 Infected Mouse Brain Activates Ionotropic Glutamate Receptors
Neurobiology of Disease, 2001 Biochemical and immunological studies have shown that mice infected with LP-BM5 virus develop antibodies to ionotropic glutamate receptors. Here, IgG isolated from brain of infected mice has been tested electrophysiologically on cultured rat cortical and
Anthony S. Basile +5 more
doaj +1 more source