Results 111 to 120 of about 44,977 (226)

Glutamate Receptor Signaling in Retina Müller Cells: Plausible Role in Neurodegeneration

Receptors
The retinal network relies on glutamate, the primary excitatory neurotransmitter involved in the visual cycle. Glutamate transactions are carried out by an array of distinct receptors and transporters distributed across both pre- and post-synaptic ...
Bolaji Oyetayo, Yurixy Mendoza-Silva, Temitayo Subair, Luisa C Hernández-Kelly, Marie-Paule Felder-Schmittbuhl, Tatiana N. Olivares-Bañuelos, Arturo Ortega   +6 more
doaj   +1 more source

The diversity of AMPA receptor inhibition mechanisms among amidine-containing compounds

Frontiers in Pharmacology
Amidine-containing compounds are primarily known as antiprotozoal agents (pentamidine, diminazene, furamidine) or as serine protease inhibitors (nafamostat, sepimostat, camostat, gabexate). DAPI is widely recognized as a fluorescent DNA stain.
Arseniy S. Zhigulin, Mikhail Y. Dron, Oleg I. Barygin, Denis B. Tikhonov   +3 more
doaj   +1 more source

Glutamate signalling in bone.

Frontiers in Endocrinology, 2012
Mechanical loading plays a key role in the physiology of bone, allowing bone to functionally adapt to its environment, however characterisation of the signalling events linking load to bone formation is incomplete.
Karen eBrakspear, Deborah eMason
doaj   +1 more source

Distinct combinations of variant ionotropic glutamate receptors mediate thermosensation and hygrosensation in Drosophila

eLife, 2016
Ionotropic Receptors (IRs) are a large subfamily of variant ionotropic glutamate receptors present across Protostomia. While these receptors are most extensively studied for their roles in chemosensory detection, recent work has implicated two family ...
Zachary A Knecht, Ana F Silbering, Lina Ni, Mason Klein, Gonzalo Budelli, Rati Bell, Liliane Abuin, Anggie J Ferrer, Aravinthan DT Samuel, Richard Benton, Paul A Garrity   +10 more
doaj   +1 more source

An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing

Nature Communications, 2018
Little is known about the role of variant ionotropic glutamate receptors (IRs) in insect taste. Here the authors characterise the expression pattern of IRs in the Drosophila gustatory system and highlight the role of one receptor, IR56d, in the detection
Juan Antonio Sánchez-Alcañiz, Ana Florencia Silbering, Vincent Croset, Giovanna Zappia, Anantha Krishna Sivasubramaniam, Liliane Abuin, Saumya Yashmohini Sahai, Daniel Münch, Kathrin Steck, Thomas O. Auer, Steeve Cruchet, G. Larisa Neagu-Maier, Simon G. Sprecher, Carlos Ribeiro, Nilay Yapici, Richard Benton   +15 more
doaj   +1 more source

Distinct subunits in heteromeric kainate receptors mediate ionotropic and metabotropic function at hippocampal mossy fiber synapses [PDF]

, 2005
Heteromeric kainate receptors (KARs) containing both glutamate receptor 6 (GluR6) and KA2 subunits are involved in KAR-mediated EPSCs at mossy fiber synapses in CA3 pyramidal cells.
Coussen, F, Mulle, C, Ruiz, A, Sachidhanandam, S, Utvik, JK   +4 more
core  

Consciousness operates beyond the timescale for discerning time intervals: implications for Q-mind theories and analysis of quantum decoherence in brain [PDF]

, 2003
This paper presents in details how the subjective time is constructed by the brain cortex via reading packets of information called "time labels", produced by the right basal ganglia that act as brain timekeeper.
Georgiev, Danko
core  

Neurotransmitter signaling in white matter [PDF]

, 2014
Butt, Arthur M., Fern, Robert F., Matute, Carlos   +2 more
core   +1 more source

Isolation and social instigation in animal models of aggression: effects of an mGLU1 receptor antagonist administration [PDF]

, 2017
Isolate-induced aggression in male mice is a model widely used in psychoparmacology of aggression. Animals are usually isolated for 30 days and subsequently treated and confronted with an anosmic opponent in a neutral area.
Martin-Lopez, Maria Mercedes
core  

Neural progenitor cell differentiation and migration : Role of glutamate signaling, brain-derived neurotrophic factor, and hypoxia/acidosis [PDF]

, 2013
The mammalian central nervous system (CNS) develops from multipotent neural stem or progenitor cells. During development the cells proliferate actively and differentiate into all the different cell types of the brain.
Jansson, Linda
core