Results 131 to 140 of about 644,252 (236)

Functional activation of glutamate ionotropic receptors in the human peripheral retina

open access: yes, 2011
Glutamate is the major neurotransmitter in the vertebrate retina. Neurons involved in the glutamate pathway express a-amino-3-hydroxyl-5-methylisoxazole-4-propionic acid (AMPA), kainic acid (KA) and Nmethyl- D-aspartate (NMDA) receptors.
Acosta Etchebarne, Monica   +6 more
core   +1 more source

The influence of zinc ions on ionotropic glutamate receptors [PDF]

open access: yes, 2015
Zinc is one of the most abundant divalent metal ion in the central nervous system, where it serves as regulator of many proteins (channels, receptors, pump...), product of neurosecretion or cofactor. The highest concentration of zinc in synaptic vesicles
Fraňková, Denisa
core  

Deeper Insights into the Allosteric Modulation of Ionotropic Glutamate Receptors

open access: yes, 2016
Two articles in this issue of Neuron (Yelshanskaya et al., 2016; Yi et al., 2016) explore the structural basis of allosteric inhibition in ionotropic glutamate receptors, providing key insights into how iGluRs function in the brain as well as how they ...
Regan, Michael C., Furukawa, Hiro
core   +1 more source

Memantine inhibits calcium-permeable AMPA receptors

open access: yesNature Communications
Memantine is an US Food and Drug Administration (FDA) approved drug that is thought to selectively inhibit NMDA-subtype of ionotropic glutamate receptors (NMDARs).
Elisa Carrillo   +6 more
doaj   +1 more source

Glutamate partner drives gamma-glutamyl-dipeptide effects on ionotropic glutamate receptors

open access: yes
International audienceGamma-glutamyl dipeptides are yielded by the condensation of glutamate with another amino acid on the gamma position. Their synthesis results from the hydrolysis of glutathione (GSH ; gamma-Glu-Cys-Gly) by gamma- glutamyl ...
Andreu, Sandro   +13 more
core   +2 more sources

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