Results 171 to 180 of about 122,014 (288)

Intracellular cholesterol transport proteins: roles in health and disease [PDF]

, 2016
Graham, Annette, Soffientini, Ugo
core   +1 more source

Therapeutic Management of LDL-C: Efficacy and Economic Impact Assessment. [PDF]

J Cardiovasc Dev Dis
Elshafeey A.
europepmc   +1 more source

Treatment of Homozygous Familial Hypercholesterolemia. [PDF]

JACC Adv
Cegla J, Walji S, Barton L, Neuwirth C, Thompson GR.   +4 more
europepmc   +1 more source

Resveratrol improved atherosclerosis by increasing LDLR levels via the EGFR-ERK1/2 signaling pathway. [PDF]

Lipids Health Dis
Hu D, Wang L, Qi L, Yang X, Jin Y, Yin H, Huang Y, Sheng J, Wang X.   +8 more
europepmc   +1 more source

GREM1 deficiency induced bone marrow adipose niche promotes B‐cell acute lymphoblastic leukemia disease progression

International Journal of Cancer, EarlyView.
What's New? Too often, children treated for B‐cell acute lymphocytic leukemia (B‐ALL) experience relapse. Here, the authors investigate the role of dyslipidemia in leukemia progression. Higher adipogenicity in bone marrow mesenchymal stem cells, and increased triglyceride accumulation, are associated with higher risk of death.
Lili Song, Rui Zhang, Liya Pan, Qiang Mi, Yi Yang, Xiang Wang, Yani Ma, Shuhong Shen, Benshang Li, Yanxin Li, Li Hong   +10 more
wiley   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

HDL-Cholesterol and Triglycerides Dynamics: Essential Players in Metabolic Syndrome. [PDF]

Antioxidants (Basel)
Alcover S, Ramos-Regalado L, Girón G, Muñoz-García N, Vilahur G.   +4 more
europepmc   +1 more source

Temporal response patterns of human gut microbiota to dietary fiber

iMeta, EarlyView.
In this study, 19 overweight participants, with or without type 2 diabetes mellitus, underwent 14 days of normal‐diet observation followed by 14 days of dietary fiber intervention. Fecal samples and continuous glucose monitoring data were collected daily throughout the 28‐day period.
Xiaotong Lin, Chaoxun Wang, Biao Liu, Yin Zhu, Rui Zhai, Chenhong Zhang   +5 more
wiley   +1 more source

High-density lipoprotein cholesterol: how studying the 'good cholesterol' could improve cardiovascular health. [PDF]

Open Biol
Diaz L, Bielczyk-Maczynska E.
europepmc   +1 more source

Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii

Journal of Applied Toxicology, EarlyView.
ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz, Shira Paz, Rotem Saban, Inbar Zuker, Hagay Shmuely, Katy Gorshkov, Jwar Meetro, Shahrzad Tafazoli, Trung Vo, Gabriela Amiram, Carmit Shani Levi, Uri Lesmes, Ilan Samish   +12 more
wiley   +1 more source