Results 101 to 110 of about 46,677 (173)

Binding Selectivity Analysis from Alchemical Receptor Hopping and Swapping Free Energy Calculations [PDF]

arXiv
We present receptor hopping and receptor swapping free energy estimation protocols based on the Alchemical Transfer Method (ATM) to model the binding selectivity of a set of ligands to two arbitrary receptors. The receptor hopping protocol, where a ligand is alchemically transferred from one receptor to another in one simulation, directly yields the ...
arxiv  

New Frontiers in Gut Nutrient Sensor Research: Nutrient Sensors in the Gastrointestinal Tract: Modulation of Sweet Taste Sensitivity by Leptin

Journal of Pharmacological Sciences, 2010
The ability to perceive sweet compounds is important for animals to detect an external carbohydrate source of calories and has a critical role in the nutritional status of animals.
Nao Horio, Masafumi Jyotaki, Ryusuke Yoshida, Keisuke Sanematsu, Noriatsu Shigemura, Yuzo Ninomiya   +5 more
doaj  

LEPTIN AND OBESITY – NEUROENDOCRINE , METABOLIC AND ATHEROGENIC EFFECTS OF LEPTIN

Zdravniški Vestnik, 2003
Background. Leptin is an adipocyte-derived hormone that was recently discovered. Leptin and leptin resistance play an important role in the pathogenesis of obesity.
Mišo Šabovič, Alenka Mavri
doaj  

Obesity, White Adipose Tissue, and Adipokines Signaling in Male Reproduction. [PDF]

Mol Nutr Food Res
Martins FF, Amarante MDSM, Oliveira DS, Vasques-Monteiro IML, Souza-Mello V, Daleprane JB, Camillo CDS.   +6 more
europepmc   +1 more source

Leptin regulates parathyroid hormone secretion through CaSR-ERK1/2 signaling. [PDF]

FASEB J
Kilav-Levin R, Hassan A, Melloul D, Naveh-Many T.   +3 more
europepmc   +1 more source

The ventral premammillary nucleus at the interface of environmental cues and social behaviors. [PDF]

Front Neurosci
Cavalcante JC, da Silva FG, Sáenz de Miera C, Elias CF.   +3 more
europepmc   +1 more source

Alterations in the inflammatory markers of the Tumor Necrosis Factor system in overweight and obese children and adolescents. [PDF]

PLoS One
Palhares HMDC, da Silva AP, Tomé JM, da Silva MV, Rodrigues Júnior V, Ribeiro FA, Oliveira MM, Fonseca ECR, Valle IA, Borges MF.   +9 more
europepmc   +1 more source

The effect of garlic and stevia extract with aerobic exercise on hypothalamic leptin and ghrelin receptor mRNA expression and insulin resistance in obese rats. [PDF]

BMC Complement Med Ther
Amirkhani Z, Gholi AM, Asghari S, Hakak D, Pouryousef M, Yahyaei B, Ziaolhagh SJ.   +6 more
europepmc   +1 more source

Mechanisms through which laparoscopic sleeve gastrectomy mitigates atherosclerosis risk: a focus on visceral adipose tissue. [PDF]

Eur J Med Res
Xu J, Wang H, Han B, Zhang X.
europepmc   +1 more source

Metabolic control of ovarian function through the sympathetic nervous system: role of leptin. [PDF]

Front Endocrinol (Lausanne)
Astudillo-Guerrero C, Paredes AH, Escobar J, Fernandois D, Barra R, Cruz G.   +5 more
europepmc   +1 more source