Transport of BMAA into Neurons and Astrocytes by System x\u3csub\u3ec\u3c/sub\u3e- [PDF]
The study of the mechanism of β-N-methylamino-l-alanine (BMAA) neurotoxicity originally focused on its effects at the N-methyl-d-aspartate (NMDA) receptor. In recent years, it has become clear that its mechanism of action is more complicated.
Albano, Rebecca, Lobner, Doug
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Retrospective analysis reveals significant association of hypoglycemia with tramadol and methadone in contrast to other opioids. [PDF]
Tramadol is one of the most commonly used analgesics worldwide, classified as having a low abuse potential by U.S. Drug Enforcement Agency, and often recommended in pain management guidelines.
Abagyan, Ruben+3 more
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Mental and behavioral disorders and limb twitch for five months
DOI: 10.3969/j.issn.1672-6731.2016.09 ...
Yi SHEN+5 more
doaj
Presynaptic NMDA receptors and spike timing-dependent long-term depression at cortical synapses
It has recently been discovered that some forms of timing-dependent long-term depression (t-LTD) require presynaptic N-methyl-D-aspartate (NMDA) receptors. In this review, we discuss the evidence for the presence of presynaptic NMDA receptors at cortical
Antonio Rodriguez Moreno+4 more
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The Effects of Serotonin on Functionally Diverse Isolated Lamprey Spinal Cord Neurons [PDF]
The experiments reported here showed that application of serotonin (5-hydroxytryptamine, 5-HT) (100 µ M) did not induce any significant current through the membranes of any of the spinal neurons studied (n = 62).
Batueva, I. V.+4 more
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Anti-N-methyl-D-aspartate receptor encephalitis combined with teratoma: two cases report
DOI: 10.3969/j.issn.1672-6731.2016.09 ...
Kun HONG+11 more
doaj
In the present study, N-methyl-D-aspartate receptor 2B (NR2B)-specific siRNA was applied in parkinsonian models. Our previous results showed that reduction in expression of N-methyl-D-aspartate receptor 1 (NR1), the key subunit of N-methyl-D-aspartate ...
Olivia T.W. Ng+3 more
doaj +1 more source
Limits of feedback control in bacterial chemotaxis
Inputs to signaling pathways can have complex statistics that depend on the environment and on the behavioral response to previous stimuli. Such behavioral feedback is particularly important in navigation.
Dufour, Yann S.+3 more
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A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System x\u3csub\u3ec\u3c/sub\u3e\u3csup\u3e−\u3c/sup\u3e Mediates Aglycemic Neuronal Cell Death [PDF]
The astrocyte cystine/glutamate antiporter (system xc−) contributes substantially to the excitotoxic neuronal cell death facilitated by glucose deprivation. The purpose of this study was to determine the mechanism by which this occurred.
He, Yan+5 more
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Epsilon ionotropic glutamate receptors (iGluRs) are a recently defined clade of neurotransmitter receptors that are found in all major metazoan lineages that are distinct from α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), kainate, delta ...
Anhadvir Singh+9 more
doaj +1 more source