D-Amino Acids in the Nervous and Endocrine Systems
Amino acids are important components for peptides and proteins and act as signal transmitters. Only L-amino acids have been considered necessary in mammals, including humans. However, diverse D-amino acids, such as D-serine, D-aspartate, D-alanine, and D-
Yoshimitsu Kiriyama, Hiromi Nochi
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Disinhibition of hippocampal CA3 neurons induced by suppression of an adenosine A1 receptor-mediated inhibitory tonus: Pre- and postsynaptic components [PDF]
Intracellular recordings were performed on hippocampal CA3 neuronsin vitro to investigate the inhibitory tonus generated by endogenously produced adenosine in this brain region.
Alzheimer+60 more
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Anti-N-methyl-D-aspartate receptor encephalitis: three cases report and review of literature
Objective To study the clinical and laboratory features and diagnosis of the patient with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis.
Guan-en ZHOU, Zhong-ping AN
doaj
Cerebral edema and excitoxicity are well known phenomena and are reported in multiple pathological contexts. Despite that, regarding traumatic brain injury, significant events in incidence and potential clinical consequences, little is known about the ...
José Luís Alves, Anabela Mota Pinto
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Anti-N-methyl-D-aspartate receptor encephalitis: analysis of three cases
Objective To study clinical features, diagnosis, therapy response and prognosis of anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis. Methods Three cases with anti-NMDAR encephalitis were reported.
Hui SU, Rong-fei WANG, Sheng-yuan YU
doaj
D-AMINO ACID OXIDASE: A REVIEW [PDF]
Over many years, D-serine and glycine were found to be the endogenous ligands for glycine-binding site for N-methyl-D-aspartate receptors. D-serinebefore being used up by the cells undergoes oxidative deamination by the enzyme D-amino acid oxidase (DAAO)
Nithya S, Ts, Shanmugarajan
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幼若ラットの視覚野皮質における長期増強とN-methyl-D-aspartate受容体 [PDF]
This is the peer reviewed version of the following article: Kimura, F, Nishigori, A, Shirokawa, T, Tsumoto, T, ( 1989), Long‐term potentiation and N‐methyl‐D‐aspartate receptors in the visual cortex of young rats..
キムラ, フミタカ, 木村, 文隆
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N-methyl-D-aspartate receptors play important roles in acquisition and expression of the eyeblink conditioned response in glutamate receptor subunit delta2 mutant mice. [PDF]
Classical eyeblink conditioning has been known to depend critically on the cerebellum. Apparently consistent with this, glutamate receptor subunit delta2 null mutant mice, which have serious morphological and functional deficiencies in the cerebellar ...
Fukunaga Satoshi+6 more
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Pediatric anti-N methyl D aspartate receptor encephalitis
Anti-N Methyl D Aspartate Receptor encephalitis (anti-NMDARE) is a recently defined disease, which is probably more under-recognized than rare. We report a case of anti-NMDARE in a 13-years-old girl, who presented with intractable seizures. To the best of our knowledge, this is the second case of pediatric anti-NMDARE being reported from India.
S K Sogani+5 more
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Subunit Arrangement in N-Methyl-d-aspartate (NMDA) Receptors [PDF]
N-Methyl-d-aspartate (NMDA) receptors, the main mediators of excitatory synaptic transmission, are heterotetrameric receptors. Typically, glycine binding NR1 subunits co-assemble with glutamate binding NR2 subunits to form a functional receptor. Here we have used luminescence resonance energy transfer (LRET) investigations to establish the specific ...
Anu Rambhadran+2 more
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