Results 41 to 50 of about 26,672 (188)
Exocytosis of ATP from astrocytes modulates phasic and tonic inhibition in the neocortex. [PDF]
PLoS Biology, 2014 Communication between neuronal and glial cells is important for many brain functions. Astrocytes can modulate synaptic strength via Ca(2+)-stimulated release of various gliotransmitters, including glutamate and ATP.
Ulyana Lalo +5 more
doaj +1 more source
Metabolic Changes Induced by Purinergic Signaling: Role in Food Intake
Frontiers in Pharmacology, 2021 The purinergic signalling has a well-established role in the regulation of energy homeostasis, but there is growing evidence of its implication in the control of food intake.
Vanni Caruso +8 more
doaj +1 more source
Mitochondria Synergize With P2 Receptors to Regulate Human T Cell Function
Frontiers in Immunology, 2020 Intracellular ATP is the universal energy carrier that fuels many cellular processes. However, immune cells can also release a portion of their ATP into the extracellular space.
Carola Ledderose, Wolfgang G. Junger
doaj +1 more source
Purinergic Signaling in Spermatogenesis
Frontiers in Endocrinology, 2022 Adenosine triphosphate (ATP) serves as the essential source of cellular energy. Over the last two decades, however, ATP has also attracted increasing interest as an extracellular signal that activates purinergic plasma membrane receptors of the P2 family.
Nadine Mundt +5 more
doaj +1 more source
Mediators of Inflammation, 2015 Purinergic mediators such as adenosine 5′-triphosphate (ATP) are released into the extracellular compartment from damaged tissues and activated immune cells. They are then recognized by multiple purinergic P2X and P2Y receptors.
Yosuke Kurashima +2 more
doaj +1 more source
Mechanisms of astrocytic and microglial purinergic signaling in homeostatic regulation and implications for neurological disease [PDF]
Exploration of NeurosciencePurinergic signaling, mediated by ATP and adenosine receptors, plays a crucial role in cellular communication and homeostasis within the central nervous system (CNS), particularly by regulating synaptic activity, glial cell functions, and neuroplasticity.
Moawiah M Naffaa
doaj +1 more source
Increased accuracy of ligand sensing by receptor diffusion on cell surface [PDF]
Physical Review E 82, 041902 (2010), 2010 The physical limit with which a cell senses external ligand concentration corresponds to the perfect absorber, where all ligand particles are absorbed and overcounting of same ligand particles does not occur. Here we analyze how the lateral diffusion of receptors on the cell membrane affects the accuracy of sensing ligand concentration.
arxiv +1 more source
Biology of Platelet Purinergic Receptors and Implications for Platelet Heterogeneity
Frontiers in Pharmacology, 2018 Platelets are small anucleated cells present only in mammals. Platelets mediate intravascular hemostatic balance, prevent interstitial bleeding, and have a major role in thrombosis.
Milka Koupenova, Katya Ravid
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Frontiers in Neuroscience, 2023 Age-related macular degeneration (AMD) is a chronic and progressive inflammatory disease of the retina characterized by photoceptor loss and significant central visual impairment due to either choroidal neovascularization or geographic atrophy.
Haydn Molcak +3 more
doaj +1 more source
Purinergic receptors on blood platelets
Platelets, 1996 Extracellular adenine nucleotides interact with P2 purinergic receptors to regulate a broad range of physiological processes among which platelet aggregation P2 purinoceptors were divided into two main groups: the G-protein coupled receptor or 'metabotropic' superfamily termed P2Y and the ligand-gated ion channel or 'ionotropic receptor' superfamily ...
J P Cazenave +5 more
openaire +3 more sources