Results 151 to 160 of about 8,231 (179)

The P2 purinergic receptors of human dendritic cells: identification and coupling to cytokine release

The FASEB Journal, 2000
ABSTRACT We investigated the expression of purinoceptors in human dendritic cells, providing functional, pharmacological, and biochemical evidence that immature and mature cells express P2Y and P2X subtypes, coupled to increase in the intracellular Ca 2+ , membrane ...
FERRARI, Davide, LA SALA A., CHIOZZI, Paola, MORELLI, ANNA, FALZONI, Simonetta, GIROLOMONI G., IDZKO M., DICHMANN S., NORGAUER J., DI VIRGILIO, Francesco   +9 more
openaire   +4 more sources

Purinergic P2 Receptors in Epilepsy

2023
Jonathon Smith, Tobias Engel
openaire   +1 more source

P2 purinergic receptor expression and function in tumor-related immune cells

Purinergic Signalling
P2 purinergic receptor expression is dysregulated in multiple cancer subtypes and is associated with worse outcomes. Studies identify roles for P2 purinergic receptors in tumor cells that drive disease aggressiveness. There is also sufficient evidence that P2 purinergic receptor expression within the tumor microenvironment (TME) is critical for disease
Vahinipriya Manoharan, Oluwafemi O. Adegbayi, Janielle P. Maynard   +2 more
openaire   +2 more sources

Purinergic P2 receptors and giant cell formation.

2000
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FALZONI, Simonetta, CHIOZZI, Paola, FERRARI, Davide, DI VIRGILIO, Francesco   +3 more
openaire   +1 more source

Unveiling the agonistic properties of Preyssler-type Polyoxotungstates on purinergic P2 receptors

Journal of Inorganic Biochemistry
The Preyssler-type polyoxotungstate ({P5W30}) belongs to the family of polyanionic metal-oxides formed by group V and VI metal ions, such as V, Mo and W, commonly known as polyoxometalates (POMs). POMs have demonstrated inhibitory effect on a significant number of ATP-binding proteins in vitro.
Poejo, Joana, Gumerova, Nadiia I., Rompel, Annette, Mata, Ana M., Aureliano, Manuel, Gutierrez-Merino, Carlos   +5 more
openaire   +3 more sources

Purinergic signalling in cancer therapeutic resistance: From mechanisms to targeting strategies

Drug Resistance Updates, 2023
Henning Ulrich, Yih-Cherng Liou, Peter Illés   +2 more
exaly  

Purine and purinergic receptors in health and disease

MedComm, 2023
Nianzhi Chen
exaly  

Cell surface localization of P2-purinergic receptors in vas deferens

Biochemical Pharmacology, 1983
R J, Head, J P, O'Donnell, G K, Hogaboom, J S, Fedan   +3 more
openaire   +2 more sources

Purinergic Signaling in the Hallmarks of Cancer

Cells, 2020
FRANCISCO G Vázquez-Cuevas, Mauricio DIAZ-MUÑOZ   +1 more
exaly  

P2 Purinergic Receptors: Modulation of Cell Function and Therapeutic Potential

The Journal of Pharmacology and Experimental Therapeutics, 2000
G, Burnstock, M, Williams
openaire   +2 more sources