Results 211 to 220 of about 28,114 (251)
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P2 purinergic receptors signal to glycogen synthase kinase‐3β in astrocytes
Journal of Neuroscience Research, 2006AbstractGlycogen synthase kinase (GSK)‐3 was identified initially as an enzyme that regulates glycogen synthesis in response to insulin, but more recent studies indicate that it is also involved in numerous cellular processes, including cell survival, cell cycle regulation, proliferation, and differentiation.
Joseph T, Neary, Yuan, Kang
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P2 purinergic receptor antagonists disrupt maternal behavior in lactating rats
Pharmacology Biochemistry and Behavior, 2017The involvement of purinergic signaling in several brain functions has been recognized, but the modulation on maternal behavior by the purinergic system is not established, even though there are functional interactions between the purinergic and oxytocinergic systems.
Luciana C. Teodoro +3 more
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International Reviews of Immunology, 2020
The nucleotide adenosine-5′-triphosphate (ATP) is mostly thought to be energy carrier, but evidence presented in multiple studies proves ATP involvement into variety of processes, due to its neuromodulatory capabilities. ATP and its metabolite—adenosine,
Marharyta Zyma, R. Pawliczak
semanticscholar +1 more source
The nucleotide adenosine-5′-triphosphate (ATP) is mostly thought to be energy carrier, but evidence presented in multiple studies proves ATP involvement into variety of processes, due to its neuromodulatory capabilities. ATP and its metabolite—adenosine,
Marharyta Zyma, R. Pawliczak
semanticscholar +1 more source
RT-PCR study of purinergic P2 receptors in hematopoietic cell lines
Biochemistry (Moscow), 2006Seven P2X and fifteen P2Y receptors have been identified to date, partly on the basis of amino acid sequence homologies. The expression of all cloned human purinergic P2 receptors was investigated on the messenger RNA level in promonocytic U937 cells, erythroblastic K562 cells, and undifferentiated, dimethyl sulfoxide-differentiated granulocytic, and ...
M K, Bernhard, K, Ulrich
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Purinergic (P2) Receptor-Operated Calcium Entry into Rat Thyroid Cells
Biochemical and Biophysical Research Communications, 1993In the epithelial cell line FRT, derived from rat thyroid, extracellular ATP, at a concentration as low as 1 x 10(-7) M, specifically increases cytosolic Ca++ two fold over the basal level of 255 +/- 45 nM. A maximum increase of 5 fold over basal is seen at 1 x 10(-5) M ATP.
S M, Aloj +3 more
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Regulation of transcervical permeability by two distinct P2 purinergic receptor mechanisms
American Journal of Physiology-Cell Physiology, 2002Micromolar concentrations of ATP stimulate biphasic change in transepithelial conductance across CaSki cultures, an acute increase (phase I response) followed by a slower decrease ( phase II response). Phase I and phase II responses involve two distinct calcium-dependent pathways, calcium mobilization and calcium influx.
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The FASEB Journal, 2000
ABSTRACT We investigated the expression of purinoceptors in human dendritic cells, providing functional, pharmacological, and biochemical evidence that immature and mature cells express P2Y and P2X subtypes, coupled to increase in the intracellular Ca 2+ , membrane ...
FERRARI, Davide +9 more
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ABSTRACT We investigated the expression of purinoceptors in human dendritic cells, providing functional, pharmacological, and biochemical evidence that immature and mature cells express P2Y and P2X subtypes, coupled to increase in the intracellular Ca 2+ , membrane ...
FERRARI, Davide +9 more
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Role of P2 receptors in normal brain development and in neurodevelopmental psychiatric disorders.
Brain Research Bulletin, 2019The purinergic signaling system, including P2 receptors, plays an important role in various central nervous system (CNS) disorders. Over the last few decades, a substantial amount of accumulated data suggest that most P2 receptor subtypes (P2X1, 2, 3, 4,
Lumei Huang +2 more
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Purinergic P2 receptors and giant cell formation.
2000---
FALZONI, Simonetta +3 more
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