Results 101 to 110 of about 13,842 (161)
On the origin of spontaneous activity in the bladder [PDF]
, 2015 ObjectivesTo characterise separately the pharmacological profiles of spontaneous contractions from the mucosa and detrusor layers of the bladder wall and to describe the relationship in mucosa between ATP release and spontaneous contractions.Materials ...
Fry, Chris H, Kushida, N
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Expression of P2 nucleotide receptors varies with age and sex in murine brain microglia
Journal of Neuroinflammation, 2009 Microglia are implicated in multiple neurodegenerative disorders, many of which display sexual dimorphisms and have symptom onsets at different ages. P2 purinergic receptors are critical for regulating various microglial functions, but little is known ...
Nikodemova Maria +2 more
doaj +1 more source
P2X and P2Y receptor signaling in red blood cells
Frontiers in Molecular Biosciences, 2015 Purinergic signaling involves the activation of cell surface P1 and P2 receptors by extracellular nucleosides and nucleotides such as adenosine and adenosine triphosphate (ATP), respectively.
Ronald eSluyter +2 more
doaj +1 more source
BMC Research Notes, 2010 Background Purines such as adenosine and ATP are now generally recognized as the regulators of many physiological functions, such as neurotransmission, pain, cardiac function, and immune responses.
Suzuki Tokiko +2 more
doaj +1 more source
The favorable kinetics and balance of nebivolol-stimulated nitric oxide and peroxynitrite release in human endothelial cells [PDF]
, 2013 Background: Nebivolol is a third-generation beta-blocker used to treat hypertension. The vasodilation properties of nebivolol have been attributed to nitric oxide (NO) release.
Corbalan, J Jose +5 more
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Virulence, 2018 Epsilon-toxin (ETX) is produced by types B and D strains of Clostridium perfringens, which cause fatal enterotoxaemia in sheep, goats and cattle. Previous studies showed that only a restricted number of cell lines are sensitive to ETX and ETX-induced ...
Jie Gao +10 more
doaj +1 more source
Functional characterization of P2Y1 and P2X4 receptors in human neuroblastoma SK-N-MC cells [PDF]
, 2015 Nucleotides are important signalling molecules in both the peripheral and central nervous system. However, the in vitro study of their receptors can be hampered by the heterogeneity of primary neuronal cultures. The use of clonal neuroblastoma cell lines
Bullido, María Jesús +5 more
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Mechanisms of ATP release and signalling in the blood vessel wall [PDF]
, 2017 The nucleotide adenosine 5′-triphosphate (ATP) has classically been considered the cell's primary energy currency. Importantly, a novel role for ATP as an extracellular autocrine and/or paracrine signalling molecule has evolved over the past century and ...
Billaud, Marie +2 more
core
The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine.
, 2015 International audienceThe NLR pyrin domain containing 3 (NLRP3) inflammasome is a major component of the innate immune system, but its mechanism of activation by a wide range of molecules remains largely unknown.
Baron, Ludivine +11 more
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