Results 111 to 120 of about 583,778 (211)

The P2X receptor mediated regulation of inhibitory synaptic transmission [PDF]

In the central nervous system ATP can be released by neurons and glial cells through similar pathways as other neurotransmitters. Extracellular ATP targets P2X purinoreceptors, causing an influx of Ca2+ ions which transmit very important messages for ...
Andrew-Adiamah, Jemma
core  

GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors-2

, 2011
.Copyright information:Taken from "GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors"http://www.biomedcentral.com/1471-2105/9/263BMC Bioinformatics 2008;9():263-263.
Chiara Parravicini (90367), Piercarlo Fantucci (44360), Maria P Abbracchio (90369), Graziella Ranghino (90368)   +3 more
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GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors-9

, 2011
.Copyright information:Taken from "GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors"http://www.biomedcentral.com/1471-2105/9/263BMC Bioinformatics 2008;9():263-263.
Chiara Parravicini (90367), Piercarlo Fantucci (44360), Maria P Abbracchio (90369), Graziella Ranghino (90368)   +3 more
core   +1 more source

GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors-7

, 2011
1 (TM3); Cys23 (Nt) and Cys269 (EL3) form an additional disulphide bridge that seems to be a peculiar feature of a restricted subgroup of GPCRs among which GPR17, P2Y and CysLT receptors.
Chiara Parravicini (90367), Piercarlo Fantucci (44360), Maria P Abbracchio (90369), Graziella Ranghino (90368)   +3 more
core   +1 more source

High glucose and free fatty acids induce beta cell apoptosis via autocrine effects of ADP acting on the P2Y(13) receptor.

, 2013
While high levels of glucose and saturated fatty acids are known to have detrimental effects on beta cell function and survival, the signalling pathways mediating these effects are not entirely known. In a previous study, we found that ADP regulates beta
Svensson, Siv, Tan, Chanyuan, Voss, Ulrikke, Erlinge, David, Olde, Björn, Erlinge, David,, Svensson, Siv,, Olde, Björn,, Lund University., Voss, Ulrikke,, Tan, Chanyuan,   +10 more
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P2RY8 (purinergic receptor P2Y, G-protein coupled, 8) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2017
Mackarel, Jill, Betts, David, Smith, Owen   +2 more
openaire   +2 more sources

P2Y2- and P2Y4 purinergic receptors are over-expressed in human colon cancer

, 2007
1. A characteristic of cancer is altered signal transduction leading to uninhibited growth. Adenosine-5'-triphosphate (ATP), a natural ligand at P2X- and P2Y purinergic receptors may regulate cell growth in non-neoplastic, as well as neoplastic tissues ...
Hultman, L., Delbro, Dick,, Nordgren, Svante,, Nylund, G.   +3 more
core  

Biochemistry of P2y-purinergic receptors.

Japanese Journal of Pharmacology, 1990
openaire   +1 more source

Rapid resensitization of purinergic receptor function in human platelets

, 2008
BACKGROUND: Adenosine diphosphate (ADP) is a critical regulator of platelet activation, mediating its actions through two G protein-coupled receptors (GPCRs), the P2Y(1) and P2Y(12) purinergic receptors.
Barton, JF, Poole, AW, Mayo-Martin, MB, Hardy, AR, Mundell, SJ   +4 more
core  

The Role of Purinergic Receptors in Retinal Function and Disease

Extracellular ATP acts as a neurotransmitter in the central and peripheral nervous systems. In this review, the role of purinergic receptors in neuronal signaling and bidirectional glial-neuronal communication in the retina will be considered.
Puthussery, Theresa, Ward, Michelle M, Fletcher, Erica L, Vessey, Kirstan A   +3 more
core   +1 more source