Results 11 to 20 of about 62,881 (303)

Bovine cumulus-granulosa cells contain biologically active retinoid receptors that can respond to retinoic acid

open access: yesReproductive Biology and Endocrinology, 2003
Retinoids, a class of compounds that include retinol and its metabolite, retinoic acid, are absolutely essential for ovarian steroid production, oocyte maturation, and early embryogenesis.
Malayer Jerry   +2 more
doaj   +2 more sources

Human nutritional relevance and suggested nutritional guidelines for vitamin A5/X and provitamin A5/X

open access: yesNutrition & Metabolism, 2023
In the last century, vitamin A was identified that included the nutritional relevant vitamin A1 / provitamin A1, as well as the vitamin A2 pathway concept.
Torsten Bohn   +4 more
doaj   +1 more source

Potential therapeutic roles of retinoids for prevention of neuroinflammation and neurodegeneration in Alzheimer’s disease

open access: yesNeural Regeneration Research, 2019
All retinoids, which can be natural and synthetic, are chemically related to vitamin A. Both natural and synthetic retinoids use specific nuclear receptors such as retinoic acid receptors and retinoid X receptors to activate specific signaling pathways ...
Bhaskar C Das   +2 more
doaj   +1 more source

NCSTN Gene Silencing Inhibits the Retinoic Acid Signaling Pathway in Human Immortalized Keratinocytes

open access: yesInternational Journal of Dermatology and Venerology, 2021
. Objective:. Acne inversa is a multifactorial chronic debilitating disease. Genetic factors are involved in 40% of patients, especially the nicastrin (NCSTN) gene.
Ying-Da Wu   +8 more
doaj   +1 more source

Effect of retinoids on nuclear retinoic acid receptors mRNA in adipose tissue of retinol-deficient rats.

open access: yesJournal of Lipid Research, 1992
In this study, we examined effects of retinol deficiency and three retinoids, all-trans-retinoic acid, 13-cis-retinoic acid, and etretin, the aromatic derivative of retinoic acid on nuclear retinoic acid receptor isoforms alpha, beta, and gamma mRNA in ...
Riaz-ul-Haq, F Chytil
doaj   +1 more source

NADPH-cytochrome P450 reductase is regulated by all-trans retinoic acid and by 1,25-dihydroxyvitamin D3 in human acute myeloid leukemia cells. [PDF]

open access: yesPLoS ONE, 2014
Acute myeloid leukemia (AML) cell lines can be driven to differentiate to monocyte-like cells by 1,25- dihydroxyvitamin D3 (1,25D) and to granulocyte-like cells by all-trans-retinoic acid (ATRA).
Elżbieta Gocek   +3 more
doaj   +1 more source

Thyroid hormone regulation of gene expression in primary cerebrocortical cells: role of thyroid hormone receptor subtypes and interactions with retinoic acid and glucocorticoids. [PDF]

open access: yesPLoS ONE, 2014
The effects of thyroid hormone on brain development and function are largely mediated by the binding of 3,5,3'-triiodo-L-thyronine (T3) to its nuclear receptors (TR) to regulate positively or negatively gene expression.
Pilar Gil-Ibáñez   +2 more
doaj   +1 more source

Cloning retinoid and peroxisome proliferator-activated nuclear receptors of the Pacific oyster and in silico binding to environmental chemicals. [PDF]

open access: yesPLoS ONE, 2017
Disruption of nuclear receptors, a transcription factor superfamily regulating gene expression in animals, is one proposed mechanism through which pollution causes effects in aquatic invertebrates.
Susanne Vogeler   +3 more
doaj   +1 more source

Beta-carotene Reduces Body Adiposity of Mice Via BCMO1 [PDF]

open access: yes, 2011
Evidence from cell culture studies indicates that ß-carotene-(BC)-derived apocarotenoid signaling molecules can modulate the activities of nuclear receptors that regulate many aspects of adipocyte physiology.
Yvonne G. J. van Helden   +54 more
core   +1 more source

Induction of lysosomal phospholipase A2 through the retinoid X receptor in THP-1 cells

open access: yesJournal of Lipid Research, 2004
An acidic phospholipase A2 (LPLA2) was recently purified and cloned. THP-1 cells were used to characterize the gene induction of LPLA2. THP-1 cells were stimulated with several differentiation agents.
Akira Abe   +3 more
doaj   +1 more source

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