Results 21 to 30 of about 49,133 (244)
Medicina, 2022 Background and Objectives: Cardiovascular (CV) risk is elevated in rheumatoid arthritis (RA). RA patient plasma causes pro-atherogenic derangements in cholesterol transport leading to macrophage foam cell formation (FCF).
Saba Ahmed +6 more
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Apoptotic cell recognition receptors and scavenger receptors [PDF]
Immunological Reviews, 2015 SummaryPhosphatidylserine recognition receptors are a highly diverse set of receptors grouped by their ability to recognize the ‘eat‐me’ signal phosphatidylserine on apoptotic cells. Most of the phosphatidylserine recognition receptors dampen inflammation by inducing the production of anti‐inflammatory mediators during the phagocytosis of apoptotic ...
Kristen K. Penberthy +1 more
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Homeostasis: A scavenger receptor for haemoglobin [PDF]
Current Biology, 2001 Recent studies have identified a macrophage-specific receptor for the clearance of haemoglobin-haptoglobin complexes, which protects the host against the toxicity of free haemoglobin.
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Innate scavenger receptor-A regulates adaptive T helper cell responses to pathogen infection
Nature Communications, 2017 Scavenger receptors can function as pattern recognition receptors to sense infection. Here the authors show that, in response to worm and bacterial infection, scavenger receptor class A prevents nuclear localization of IRF5 and thereby drives M2 ...
Zhipeng Xu +15 more
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Macrophage Scavenger Receptor Class A [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2000 Abstract—In atherogenesis, elevated plasma levels of low density lipoprotein (LDL) lead to the chronic presence of LDL in the arterial wall. There, LDL is modified (eg, oxidized), and these modified lipoproteins activate endothelial cells, which attract circulating monocytes.
Winther, M.P.J. de +3 more
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LRP: a multifunctional scavenger and signaling receptor [PDF]
Journal of Clinical Investigation, 2001 The LDL receptor–related protein (LRP) is larger than but structurally similar to other members of the LDL receptor gene family, an ancient family of endocytic receptors (1–3). Whereas the LDL receptor, the founding member of this family, appears to act solely in lipoprotein metabolism, the LRP and other members of this family appear to have other ...
Joachim Herz, Dudley K. Strickland
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The macrophage scavenger receptor CD163
Immunobiology, 2005 Mature tissue macrophages form a first line of defense to recognize and eliminate potential pathogens; these specialized cells are capable of phagocytosis, degradation of self and foreign materials, establishment of cell-cell interactions, and the production of inflammatory mediators.
Fabriek, Babs O +2 more
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Physiological and pathogenic role of scavenger receptors in humans
Медицинская иммунология, 2020 The scavenger receptors (SRs)) include > 30 different molecules structurally classified into 11 classes (A to L). They are expressed mostly on stromal macrophages, and their expression may be augmented in direct dependence with concentrations of their
E. Yu. Gusev +3 more
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Scavenger receptors in innate immunity
Current Opinion in Immunology, 2002 Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells.
Peiser, L, Mukhopadhyay, S, Gordon, S
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Journal of Clinical and Translational Science, 2019 OBJECTIVES/SPECIFIC AIMS: Scavenger receptor (SR) surface proteins are highly conserved motifs and are implicated in the uptake of nanotherapies. Gold nanoparticles functionalized with DNAzymes (DzNP) represent a promising novel nanotherapy for lung ...
Cory Sylber +4 more
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