Results 21 to 30 of about 50,187 (264)

Defective expression of scavenger receptors in celiac disease mucosa. [PDF]

open access: yesPLoS ONE, 2014
Celiac disease (CD) is a gluten sensitive enteropathy characterized by a marked infiltration of the mucosa with immune cells, over-production of inflammatory cytokines and epithelial cell damage.
Maria Laura Cupi   +13 more
doaj   +1 more source

Apoptotic cell recognition receptors and scavenger receptors [PDF]

open access: yesImmunological Reviews, 2015
SummaryPhosphatidylserine recognition receptors are a highly diverse set of receptors grouped by their ability to recognize the ‘eat‐me’ signal phosphatidylserine on apoptotic cells. Most of the phosphatidylserine recognition receptors dampen inflammation by inducing the production of anti‐inflammatory mediators during the phagocytosis of apoptotic ...
Kristen K. Penberthy   +1 more
openaire   +3 more sources

Hydroxychloroquine Effects on THP-1 Macrophage Cholesterol Handling: Cell Culture Studies Corresponding to the TARGET Cardiovascular Trial

open access: yesMedicina, 2022
Background and Objectives: Cardiovascular (CV) risk is elevated in rheumatoid arthritis (RA). RA patient plasma causes pro-atherogenic derangements in cholesterol transport leading to macrophage foam cell formation (FCF).
Saba Ahmed   +6 more
doaj   +1 more source

Homeostasis: A scavenger receptor for haemoglobin [PDF]

open access: yesCurrent Biology, 2001
Recent studies have identified a macrophage-specific receptor for the clearance of haemoglobin-haptoglobin complexes, which protects the host against the toxicity of free haemoglobin.
openaire   +3 more sources

Innate scavenger receptor-A regulates adaptive T helper cell responses to pathogen infection

open access: yesNature Communications, 2017
Scavenger receptors can function as pattern recognition receptors to sense infection. Here the authors show that, in response to worm and bacterial infection, scavenger receptor class A prevents nuclear localization of IRF5 and thereby drives M2 ...
Zhipeng Xu   +15 more
doaj   +1 more source

LRP: a multifunctional scavenger and signaling receptor [PDF]

open access: yesJournal of Clinical Investigation, 2001
The LDL receptor–related protein (LRP) is larger than but structurally similar to other members of the LDL receptor gene family, an ancient family of endocytic receptors (1–3). Whereas the LDL receptor, the founding member of this family, appears to act solely in lipoprotein metabolism, the LRP and other members of this family appear to have other ...
Joachim Herz, Dudley K. Strickland
openaire   +2 more sources

Direct imaging of lateral movements of AMPA receptors inside synapses [PDF]

open access: yesEMBO J 22, 18 (15/09/2003) 4656-65, 2007
Trafficking of AMPA receptors in and out of synapses is crucial for synaptic plasticity. Previous studies have focused on the role of endo/exocytosis processes or that of lateral diffusion of extra-synaptic receptors. We have now directly imaged AMPAR movements inside and outside synapses of live neurons using single-molecule fluorescence microscopy ...
arxiv   +1 more source

The macrophage scavenger receptor CD163

open access: yesImmunobiology, 2005
Mature tissue macrophages form a first line of defense to recognize and eliminate potential pathogens; these specialized cells are capable of phagocytosis, degradation of self and foreign materials, establishment of cell-cell interactions, and the production of inflammatory mediators.
Fabriek, Babs O   +2 more
openaire   +4 more sources

3582 Scavenger Receptor Expression is Differentially Affected by DNAzyme-Gold Nanoparticle Conjugates

open access: yesJournal of Clinical and Translational Science, 2019
OBJECTIVES/SPECIFIC AIMS: Scavenger receptor (SR) surface proteins are highly conserved motifs and are implicated in the uptake of nanotherapies. Gold nanoparticles functionalized with DNAzymes (DzNP) represent a promising novel nanotherapy for lung ...
Cory Sylber   +4 more
doaj   +1 more source

Effect of Rain Scavenging on Altitudinal Distribution of Soluble Gaseous Pollutants in the Atmosphere [PDF]

open access: yes, 2010
We suggest a model of rain scavenging of soluble gaseous pollutants in the atmosphere. It is shown that below-cloud gas scavenging is determined by non-stationary convective diffusion equation with the effective Peclet number. The obtained equation was analyzed numerically in the case of log-normal droplet size distribution.
arxiv   +1 more source

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