A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease [PDF]
, 2017 Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a diverse variety of ligands ...
Acton +46 more
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Journal of Lipid Research, 2005 Scavenger receptors were originally defined by their ability to bind and internalize modified lipoproteins. Macrophages express at least six structurally different cell surface receptors for modified forms of LDL that contribute to foam cell formation in
David R. Greaves, Siamon Gordon
doaj +1 more source
CXCL16 and oxLDL are induced in the onset of diabetic nephropathy [PDF]
, 2009 Diabetic nephropathy (DN) is a major cause of end-stage renal failure worldwide. Oxidative stress has been reported to be a major culprit of the disease and increased oxidized low density lipoprotein (oxLDL) immune complexes were found in patients with ...
Abdel-Aziz, Abdel-Aziz H. +11 more
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More Than Just a Removal Service: Scavenger Receptors in Leukocyte Trafficking
Frontiers in Immunology, 2018 Scavenger receptors are a highly diverse superfamily of proteins which are grouped by their inherent ability to bind and internalize a wide array of structurally diverse ligands which can be either endogenous or exogenous in nature.
Daniel A. Patten, Shishir Shetty
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Loss of Function of Scavenger Receptor SCAV-5 Protects C. elegans Against Pathogenic Bacteria
Frontiers in Cellular and Infection Microbiology, 2021 Scavenger receptors play a critical role in innate immunity by acting as the pattern-recognition receptors. There are six class B scavenger receptors homologs in C. elegans.
Aixiao Luo +5 more
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The macrophage scavenger receptor at 30 years of age: current knowledge and future challenges
Journal of Lipid Research, 2009 It is now thirty years since the original observation that macrophages take up and degrade modified forms of low density lipoprotein (LDL). Molecular cloning has identified multiple scavenger receptors that can endocytose modified LDL and binding studies
David R. Greaves, Siamon Gordon
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Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. [PDF]
, 2012 BACKGROUND The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of ...
Carl Cotman +8 more
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Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I. [PDF]
, 2006 In the past several years, a number of cellular proteins have been identified as candidate entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection.
Barth, Heidi +4 more
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Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission [PDF]
, 2010 Hepatitis C virus (HCV) can initiate infection by cell-free particle and cell-cell contact-dependent transmission. In this study we use a novel infectious coculture system to examine these alternative modes of infection.
Balfe, Peter +12 more
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International Journal of Hypertension, 2010 Scavenger receptors act as membrane-bound and soluble proteins that bind to macromolecular complexes and pathogens. This diverse supergroup of proteins mediates binding to modified lipoprotein particles which regulate the initiation and progression of ...
Sam L. Stephen +7 more
doaj +1 more source