Functional characterization of TGFβ/BMP receptors in Echinococcus granulosus sensu stricto: implications for parasite survival and therapeutic targeting [PDF]
Microbiology SpectrumCystic echinococcosis (CE), a zoonosis caused by the larval stage of the tapeworm Echinococcus granulosus sensu lato (E. granulosus s.l.), remains a global health burden.
Liang Li +7 more
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Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy [PDF]
Kidney360, 2021 Abstract Key Points TGF-β receptor 3 (TGFBR3) staining identifies a novel type of membranous nephropathy (MN).TGFBR3-associated MN is enriched in patients with membranous lupus nephritis with similar characteristics as exostosin 1/2- and neural cell adhesion molecule 1–associated MN ...
Tiffany N. Caza +9 more
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Brazilian Neurosurgery, 2023 Introduction High-grade primary brain tumors cause serious morbidity and mortality. This study aimed to investigate the role of transforming growth factor beta (TGF-β) and suppressor of mothers against decapentaplegic (Smad) receptors in high-grade ...
Güven Gürsoy +4 more
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Recent Topics in Fibrodysplasia Ossificans Progressiva [PDF]
Endocrinology and Metabolism, 2018 Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease that is characterized by the formation of heterotopic bone tissues in soft tissues, such as skeletal muscle, ligament, and tendon.
Takenobu Katagiri +3 more
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GDF-15 Inhibits ADP-Induced Human Platelet Aggregation through the GFRAL/RET Signaling Complex
Biomolecules, 2023 Growth differentiation factor-15 (GDF-15) is proposed to be strongly associated with several cardiovascular diseases, such as heart failure and atherosclerosis.
Baikang Xie +7 more
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Induction of transforming growth factor beta receptors following focal ischemia in the rat brain. [PDF]
PLoS ONE, 2014 Transforming growth factor-βs (TGF-βs) regulate cellular proliferation, differentiation, and survival. TGF-βs bind to type I (TGF-βRI) and II receptors (TGF-βRII), which are transmembrane kinase receptors, and an accessory type III receptor (TGF-βRIII ...
Gabriella Pál +2 more
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Latent transforming growth factor binding protein 4 regulates transforming growth factor beta receptor stability [PDF]
Human Molecular Genetics, 2015 Mutations in the gene for the latent transforming growth factor beta binding protein 4 (LTBP4) cause autosomal recessive cutis laxa type 1C. To understand the molecular disease mechanisms of this disease, we investigated the impact of LTBP4 loss on transforming growth factor beta (TGFβ) signaling.
Chi-Ting, Su +9 more
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TGFBR3 (transforming growth factor, beta receptor III) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on TGFBR3 (transforming growth factor, beta receptor III), with data on DNA, on the protein encoded, and where the gene is implicated.
Gatza, CE, Rawson, D, Blobe, GC
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LTBP4 affects renal fibrosis by influencing angiogenesis and altering mitochondrial structure
Cell Death and Disease, 2021 Transforming growth factor beta (TGFβ) signalling regulates extracellular matrix accumulation known to be essential for the pathogenesis of renal fibrosis; latent transforming growth factor beta binding protein 4 (LTBP4) is an important regulator of TGFβ
Chi-Ting Su +7 more
doaj +1 more source
Role of transforming growth factor-β1 in breast carcinogenesis [PDF]
Archive of Oncology, 2006 The main objective of this presentation is to review current knowledge regarding molecular mechanisms of Transforming Growth Factor-β1(TGF-ß1) action in breast carcinogenesis.
Ivanović Vesna +3 more
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