Results 121 to 130 of about 26,499 (240)

General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles

Molecular Imaging, 2011
Molecular imaging has moved to the forefront of drug development and biomedical research. The identification of appropriate imaging targets has become the touchstone for the accurate diagnosis and prognosis of human cancer. Particularly, cell surface- or
Yongliang Yang, S. James Adelstein, Amin I. Kassis   +2 more
doaj   +1 more source

Mental stress in atopic dermatitis--neuronal plasticity and the cholinergic system are affected in atopic dermatitis and in response to acute experimental mental stress in a randomized controlled pilot study.

PLoS ONE, 2014
RationaleIn mouse models for atopic dermatitis (AD) hypothalamus pituitary adrenal axis (HPA) dysfunction and neuropeptide-dependent neurogenic inflammation explain stress-aggravated flares to some extent.
Eva Milena Johanne Peters, Anna Michenko, Jörg Kupfer, Wolfgang Kummer, Silke Wiegand, Volker Niemeier, Nikolay Potekaev, Andrey Lvov, Uwe Gieler   +8 more
doaj   +1 more source

Experimental infection of horses with African horse sickness virus results in overt disseminated intravascular coagulation

Equine Veterinary Journal, Volume 58, Issue 2, Page 619-629, March 2026.
Abstract Background African horse sickness (AHS), caused by the vector‐borne African horse sickness virus (AHSV), is endemic to sub‐Saharan Africa and infection results in high mortality in naïve equine populations. Clinical signs include submucosal petechiae and prolonged bleeding post venepuncture indicative of hypocoagulation.
Eva Christina Schliewert, Emma H. Hooijberg, Amelia Goddard   +2 more
wiley   +1 more source

Soluble Urokinase Plasminogen Activator Receptor (SuPAR) Analysis for Diagnosis of Periprosthetic Joint Infection

Antibiotics
Soluble urokinase plasminogen activator receptors (suPARs) are a biomarker for inflammatory diseases. This study aims to investigate its diagnostic properties regarding periprosthetic joint infections (PJI). This retrospective cohort study included adult
Sebastian M. Klim, Jürgen Prattes, Florian Amerstorfer, Tobias Niedrist, Christoph Zurl, Martin Stradner, Barbara Dreo, Gunther Glehr, Andreas Leithner, Mathias Glehr, Patrick Reinbacher, Patrick Sadoghi, Georg Hauer   +12 more
doaj   +1 more source

HIV-1 infected lymphoid organs upregulate expression and release of the cleaved form of uPAR that modulates chemotaxis and virus expression.

PLoS ONE, 2013
Cell-associated receptor for urokinase plasminogen activator (uPAR) is released as both full-length soluble uPAR (suPAR) and cleaved (c-suPAR) form that maintain ability to bind to integrins and other receptors, thus triggering and modulating cell ...
Manuela Nebuloni, Lidia Zawada, Angelita Ferri, Antonella Tosoni, Pietro Zerbi, Massimo Resnati, Guido Poli, Luca Genovese, Massimo Alfano   +8 more
doaj   +1 more source

Piezo1‐Mediated Mechanotransduction: Orchestrating the Dynamic Response of Podocytes and Parietal Epithelial Cells to Mechanical Stress

Acta Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim The glomerulus is a specialized microvascular unit that filters plasma through the coordinated function of podocytes and parietal epithelial cells (PECs). From this perspective, the glomerulus functions like a living hydrogeological filtration system.
Maria Elena Melica, Giulia Antonelli, Anna Julie Peired, Laura Lasagni   +3 more
wiley   +1 more source

Solution structure and phylogenetics of Prod1, a member of the three-finger protein superfamily implicated in salamander limb regeneration.

PLoS ONE, 2009
BackgroundFollowing the amputation of a limb, newts and salamanders have the capability to regenerate the lost tissues via a complex process that takes place at the site of injury.
Acely Garza-Garcia, Richard Harris, Diego Esposito, Phillip B Gates, Paul C Driscoll   +4 more
doaj   +1 more source

Tristetraprolin Inhibits the Growth of Human Glioma Cells through Downregulation of Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor mRNAs

Molecules and Cells, 2015
Urokinase plasminogen activator (uPA) and urokinase plasminogen activator receptor (uPAR) play a major role in the infiltrative growth of glioblastoma. Downregulatoion of the uPA and uPAR has been reported to inhibit the growth glioblastoma. Here, we demonstrate that tristetraprolin (TTP) inhibits the growth of U87MG human glioma cells through ...
Jinhyun, Ryu, Nal Ae, Yoon, Yeon Kyung, Lee, Joo Yeon, Jeong, Seokmin, Kang, Hyemin, Seong, Jungil, Choi, Nammi, Park, Nayoung, Kim, Wha Ja, Cho, Sun Ha, Paek, Gyeong Jae, Cho, Wan Sung, Choi, Jae-Yong, Park, Jeong Woo, Park, Sang Soo, Kang   +15 more
openaire   +3 more sources

Placental Protein Release and Uptake From the Fetal Circulation in Healthy Term Pregnancies—A Human In Vivo Exploratory Study

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Fetal‐placental communication was explored by comparing protein abundances in paired umbilical artery and vein samples, using the SomaLogic 5000‐plex platform. 766 proteins were identified as released by the placenta, largely supported by placental gene expression patterns reported in transcriptomic studies.
Hilde Bastøe Sellevoll, Ina Jungersen Andresen, Ane Cecilie Westerberg, Maren‐Helene Langeland Degnes, Thor Ueland, Manuela Zucknick, Trond Melbye Michelsen   +6 more
wiley   +1 more source

Soluble urokinase-type plasminogen activator receptor as a measure of treatment response in acute exacerbation of COPD

Jornal Brasileiro de Pneumologia
Objective: To evaluate the value of soluble urokinase-type plasminogen activator receptor (suPAR) in the diagnosis of acute exacerbation of COPD (AECOPD) and in monitoring treatment response, analyzing the relationship between suPAR and fibrinogen in ...
Gehan Hassan AboEl-Magd, Maaly Mohamed Mabrouk   +1 more
doaj   +1 more source