Results 101 to 110 of about 676,629 (244)

Involvement of Urokinase-Type Plasminogen Activator in Acantholysis Induced by Pemphigus IgG [PDF]

, 1987
Pemphigus IgG induces acantholysis in skin organ culture without the involvement of complement. Urokinase-type plasminogen activator, a proteolytic enzyme, has been implicated in the development of acantholysis.
Morioka, Shinji, Lazarus, Gerald S., Jensen, Pamela J.   +2 more
core   +1 more source

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

Urokinase and type I plasminogen activator inhibitor production by normal human hepatocytes: modulation by inflammatory agents

, 1994
We examined the effects of inflammatory cytokines (interleukin-1 beta, tumor necrosis factor-alpha and transforming growth factor-beta) on the plasminogen activator system (urokinase, tissue-type plasminogen activator, type 1 plasminogen activator ...
Chesne, C., Belin, D., Guillouzo, A., Hyafil, F., Nicodeme, E., Busso, N.   +5 more
core   +3 more sources

Soluble Urokinase Plasminogen Activator Receptor (SuPAR) Analysis for Diagnosis of Periprosthetic Joint Infection

Antibiotics
Soluble urokinase plasminogen activator receptors (suPARs) are a biomarker for inflammatory diseases. This study aims to investigate its diagnostic properties regarding periprosthetic joint infections (PJI). This retrospective cohort study included adult
Sebastian M. Klim, Jürgen Prattes, Florian Amerstorfer, Tobias Niedrist, Christoph Zurl, Martin Stradner, Barbara Dreo, Gunther Glehr, Andreas Leithner, Mathias Glehr, Patrick Reinbacher, Patrick Sadoghi, Georg Hauer   +12 more
doaj   +1 more source

General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles

Molecular Imaging, 2011
Molecular imaging has moved to the forefront of drug development and biomedical research. The identification of appropriate imaging targets has become the touchstone for the accurate diagnosis and prognosis of human cancer. Particularly, cell surface- or
Yongliang Yang, S. James Adelstein, Amin I. Kassis   +2 more
doaj   +1 more source

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Immunohistochemical staining of urokinase plasminogen activator-like and urokinase plasminogen activator receptor-like proteins in the urinary tract of healthy dogs

, 2006
OBJECTIVE: To determine distribution of urokinase plasminogen activator-like protein and urokinase plasminogen activator receptor-like protein in urinary tract tissues of healthy dogs. ANIMALS: 11 healthy dogs. PROCEDURES: Necropsy specimens from kidney,
Hosgood, Giselle, Bailey, Trina R, Sehgal, Inder, Paulsen, Daniel B   +3 more
core   +1 more source

Soluble urokinase-type plasminogen activator receptor as a measure of treatment response in acute exacerbation of COPD

Jornal Brasileiro de Pneumologia
Objective: To evaluate the value of soluble urokinase-type plasminogen activator receptor (suPAR) in the diagnosis of acute exacerbation of COPD (AECOPD) and in monitoring treatment response, analyzing the relationship between suPAR and fibrinogen in ...
Gehan Hassan AboEl-Magd, Maaly Mohamed Mabrouk   +1 more
doaj   +1 more source

Mental stress in atopic dermatitis--neuronal plasticity and the cholinergic system are affected in atopic dermatitis and in response to acute experimental mental stress in a randomized controlled pilot study.

PLoS ONE, 2014
RationaleIn mouse models for atopic dermatitis (AD) hypothalamus pituitary adrenal axis (HPA) dysfunction and neuropeptide-dependent neurogenic inflammation explain stress-aggravated flares to some extent.
Eva Milena Johanne Peters, Anna Michenko, Jörg Kupfer, Wolfgang Kummer, Silke Wiegand, Volker Niemeier, Nikolay Potekaev, Andrey Lvov, Uwe Gieler   +8 more
doaj   +1 more source

Obesity‐Related Coagulation Activation in Adolescents and Children: A Systematic Review and Meta‐Analysis

Obesity Reviews, Volume 27, Issue 10, October 2026.
Obesity is widely recognized as a pro‐thrombotic condition, yet the specific biomarker profile reflecting coagulation activation remains incompletely defined. Obesity is associated with increased coagulation activation, particularly in children, suggesting an early pro‐thrombotic shift.
Julia Buchold, Hans‐Jonas Meyer, Manuel Florian Struck, Shrey Kohli, Akash Mathew, Gyulten Mangova, Alexey Surov, Matthias Blüher, Berend Isermann, Silke Zimmermann   +9 more
wiley   +1 more source