Results 101 to 110 of about 729,299 (226)

Soluble Urokinase Plasminogen Activator Receptor (SuPAR) Analysis for Diagnosis of Periprosthetic Joint Infection

Antibiotics
Soluble urokinase plasminogen activator receptors (suPARs) are a biomarker for inflammatory diseases. This study aims to investigate its diagnostic properties regarding periprosthetic joint infections (PJI). This retrospective cohort study included adult
Sebastian M. Klim, Jürgen Prattes, Florian Amerstorfer, Tobias Niedrist, Christoph Zurl, Martin Stradner, Barbara Dreo, Gunther Glehr, Andreas Leithner, Mathias Glehr, Patrick Reinbacher, Patrick Sadoghi, Georg Hauer   +12 more
doaj   +1 more source

General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles

Molecular Imaging, 2011
Molecular imaging has moved to the forefront of drug development and biomedical research. The identification of appropriate imaging targets has become the touchstone for the accurate diagnosis and prognosis of human cancer. Particularly, cell surface- or
Yongliang Yang, S. James Adelstein, Amin I. Kassis   +2 more
doaj   +1 more source

Soluble urokinase-type plasminogen activator receptor as a measure of treatment response in acute exacerbation of COPD

Jornal Brasileiro de Pneumologia
Objective: To evaluate the value of soluble urokinase-type plasminogen activator receptor (suPAR) in the diagnosis of acute exacerbation of COPD (AECOPD) and in monitoring treatment response, analyzing the relationship between suPAR and fibrinogen in ...
Gehan Hassan AboEl-Magd, Maaly Mohamed Mabrouk   +1 more
doaj   +1 more source

Mental stress in atopic dermatitis--neuronal plasticity and the cholinergic system are affected in atopic dermatitis and in response to acute experimental mental stress in a randomized controlled pilot study.

PLoS ONE, 2014
RationaleIn mouse models for atopic dermatitis (AD) hypothalamus pituitary adrenal axis (HPA) dysfunction and neuropeptide-dependent neurogenic inflammation explain stress-aggravated flares to some extent.
Eva Milena Johanne Peters, Anna Michenko, Jörg Kupfer, Wolfgang Kummer, Silke Wiegand, Volker Niemeier, Nikolay Potekaev, Andrey Lvov, Uwe Gieler   +8 more
doaj   +1 more source

Urokinase Plasminogen Activator and Urokinase Plasminogen Activator Receptor Mediate Human Stem Cell Tropism to Malignant Solid Tumors

Stem Cells, 2008
Abstract Human neural and mesenchymal stem cells have been identified for cell-based therapies in regenerative medicine and as vehicles for delivering therapeutic agents to areas of injury and tumors. However, the signals required for homing and recruitment of stem cells to these sites are not well understood.
Margarita, Gutova, Joseph, Najbauer, Richard T, Frank, Stephen Edward, Kendall, Anna, Gevorgyan, Marianne Z, Metz, Mark, Guevorkian, Marissa, Edmiston, Donghong, Zhao, Carlotta A, Glackin, Seung U, Kim, Karen S, Aboody   +11 more
openaire   +2 more sources

HIV-1 infected lymphoid organs upregulate expression and release of the cleaved form of uPAR that modulates chemotaxis and virus expression.

PLoS ONE, 2013
Cell-associated receptor for urokinase plasminogen activator (uPAR) is released as both full-length soluble uPAR (suPAR) and cleaved (c-suPAR) form that maintain ability to bind to integrins and other receptors, thus triggering and modulating cell ...
Manuela Nebuloni, Lidia Zawada, Angelita Ferri, Antonella Tosoni, Pietro Zerbi, Massimo Resnati, Guido Poli, Luca Genovese, Massimo Alfano   +8 more
doaj   +1 more source

Regulation of skeletal muscle regeneration by macrophages and the urokinase-type plasminogen activator.

, 2007
Regulation of skeletal muscle regeneration by macrophages and the urokinase-type plasminogen ...
Scott C. Bryer (7949129)
core   +2 more sources

Urokinase-type plasminogen activator receptor

, 2003
A polypeptide presenting an epitope cross-reactive with an epitope of urokinase-type plasminogen activator receptor, and/or having uPA binding activity, is described.
Pollanen,, Jari, Vaheri,, Antti, Dano, Keld, Pyke, Charles, Masucci, Maria, Teresa, Roldan, Ann, Louring, Behrendt, Niels, Ploug, Michael, Cubellis, Maria, Vittoria, Ronne, Ebbe, Tapiovaara,, Hannele, Lund Leif, Roge, Patthy, Laszlo, Salonen,, Eeva-Marjatta, Moller Lisbeth, Birk, Ellis, Vincent, Stephens, Ross, W, Blasi, Francesco, Appella,, Ettore, Schleuning,, Wolf-Dieter, Kristensen, Peter   +20 more
core  

The inactivation of single-chain urokinase-type plasminogen activator by thrombin on cultured human endothelial cells

, 2000
Single-chain urokinase-type plasminogen activator (scu-PA) is cleaved by thrombin, resulting in an inactive molecule called thrombin-cleaved two-chain urokinase-type plasminogen activator (tcu-PA/T). There is no knowledge about cell-mediated inactivation
Collen, A., Rijken, D.C., Grimbergen, J.M., Jie, A.F.H., Braat, E.A.M.   +4 more
core  

Role of specific membrane receptors in urokinase dependent migration of human keratinocytes

, 1990
On the basis of both 125I-labeled plasminogen activator binding analysis and transmission electron microscopy studies of the interaction of a plasminogen activator/gold complex with cell membranes, we have found that human keratinocytes have specific ...
Lotti, T., Dini, Germana, Del Rosso, M., Grappone, Cecilia, Fimiani, M., Magnelli, Lucia, Pucci, Marco, Fibbi, G., Caldini, Riccardo, Panconesi, Emiliano, Dini, G., Pucci, M., Fibbi, Gabriella, Panconesi, E., Del Rosso, Mario, Caldini, R., Magnelli, L., Lotti, Torello, Grappone, C.   +18 more
core   +1 more source