Results 121 to 130 of about 14,304 (250)

Modulation of CD44 Activity by A6-Peptide

Frontiers in Immunology, 2015
Hyaluronan (HA) is a nonsulfated glycosaminoglycan distributed throughout the extracellular matrix that plays a major role in cell adhesion, migration, and proliferation. CD44, a multifunctional cell surface glycoprotein, is a receptor for HA.
Malcolm eFinlayson
doaj   +1 more source

Epidermal growth factor-binding protein activates soluble and receptor-bound single chain urokinase-type plasminogen activator

, 1995
Epidermal growth factor-binding protein (EGF-BP) is a serine proteinase that reversibly associates with epidermal growth factor (EGF). We analyzed the reaction of EGF-BP with urokinase type plasminogen activator (u-PA), a serine proteinase that promotes ...
Wolf, Beni B., Brown, Morry D., Beni B. Wolf, Morry D. Brown   +3 more
core   +1 more source

Soluble gC1qR is an autocrine signal that induces B1R expression on endothelial cells [PDF]

, 2014
Bradykinin (BK) is one of the most potent vasodilator agonists known and belongs to the kinin family of proinflammatory peptides. BK induces its activity via two G protein-coupled receptors: BK receptor 1 (B1R) and BK receptor 2.
Ramadass, M, Kishore, U, Ji, Y, Pednekar, L, Peerschke, EIB, Ghebrehiwet, B, David, H, Galanakis, DK, Valentino, A, Kew, RR, Hosszu, KH   +10 more
core   +1 more source

Obesity‐Related Coagulation Activation in Adolescents and Children: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
Obesity is widely recognized as a pro‐thrombotic condition, yet the specific biomarker profile reflecting coagulation activation remains incompletely defined. Obesity is associated with increased coagulation activation, particularly in children, suggesting an early pro‐thrombotic shift.
Julia Buchold, Hans‐Jonas Meyer, Manuel Florian Struck, Shrey Kohli, Akash Mathew, Gyulten Mangova, Alexey Surov, Matthias Blüher, Berend Isermann, Silke Zimmermann   +9 more
wiley   +1 more source

Real-Time Reverse-Transcription PCR to Quantify a Panel of 19 Genes in Breast Cancer: Relationships with Sentinel Lymph Node Invasion

The International Journal of Biological Markers, 2008
At the Centre Oscar Lambret, the anticancer centre of the North of France, sentinel lymph node (SLN) procedures are routinely performed for localized (T0–T1, N0, M0) breast carcinoma without any previous treatment, in order to prevent the deleterious ...
F. Révillion Dr., Ph.D., V. Lhotellier, L. Hornez, A. Leroy, M.C. Baranzelli, S. Giard, J. Bonneterre, J.P. Peyrat   +7 more
doaj   +1 more source

Physiology and pathophysiology of the plasminogen system in the kidney [PDF]

, 2017
The plasminogen system is important for fibrinolysis in addition to tissue remodeling and inflammation with significance for kidney disease. The system consists of the circulating zymogen plasminogen (Plg) and the tissue- and urokinase-type plasminogen ...
Per Svenningsen, Rikke Ydegaard, Langkilde, Rikke Zachar, Boye L. Jensen, Hinrichs, Gitte Rye, Gitte Rye Hinrichs, Rikke Zachar, Svenningsen, Per; id_orcid, Ydegaard, Rikke, Jensen, Boye L.   +9 more
core   +1 more source

Soluble Urokinase Plasminogen Activator Receptor as a Marker for Use of Antidepressants

PLoS ONE, 2014
Inflammation is involved in the pathogenesis of depression. A few cross-sectional population-based studies have found that depression is associated with increased levels of inflammatory markers. Soluble urokinase plasminogen activation receptor (suPAR) is known to be a stable marker for inflammation.
Haastrup, Eva, Grau, Katrine, Eugen-Olsen, Jesper, Thorball, Christian, Kessing, Lars Vedel, Ullum, Henrik   +5 more
openaire   +5 more sources

Radiometallated peptides targeting guanylate cyclase C and the urokinase-type plasminogen activator receptor

, 2010
Research is currently underway worldwide into the development of receptor-specific radiopharmaceuticals for the imaging and treatment of cancer. The successful clinical development of radiolabeled somatostatin analogs for imaging and treatment of ...
Snigdha Praharaj, Michael F Giblin, Douglas Overbey   +2 more
core   +1 more source

Photobiomodulation restores blood–brain barrier integrity after hypoxia via endothelial von Willebrand factor modulation in a humanised tricellular transwell model

The Journal of Physiology, EarlyView.
Abstract figure legend Photobiomodulation restores blood–brain barrier (BBB) integrity following hypoxic stress. A multicellular human BBB model comprising brain microvascular endothelial cells, astrocytes and pericytes was established in a transwell system and subjected to acute hypoxia.
Mirriam Domocos, Denis E. Bragin, Nagesh C. Shanbhag, Luise Schlotterose, Mootaz M. Salman   +4 more
wiley   +1 more source

General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles

Molecular Imaging, 2011
Molecular imaging has moved to the forefront of drug development and biomedical research. The identification of appropriate imaging targets has become the touchstone for the accurate diagnosis and prognosis of human cancer. Particularly, cell surface- or
Yongliang Yang, S. James Adelstein, Amin I. Kassis   +2 more
doaj   +1 more source