Results 11 to 20 of about 12,788 (278)
Archaeal tyrosine recombinases
FEMS Microbiology Reviews, 2021 International audienceABSTRACT The integration of mobile genetic elements into their host chromosome influences the immediate fate of cellular organisms and gradually shapes their evolution.
Jacques Oberto +5 more
core +3 more sources
Plant DNA Recombinases: A Long Way to Go
Journal of Nucleic Acids, 2010 DNA homologous recombination is fundamental process by which two homologous DNA molecules exchange the genetic information for the generation of genetic diversity and maintain the genomic integrity.
Rajani Kant Chittela +1 more
doaj +2 more sources
Stimulation of homologous recombination in plants expressing heterologous recombinases [PDF]
BMC Plant Biology, 2020 Background Current excitement about the opportunities for gene editing in plants have been prompted by advances in CRISPR/Cas and TALEN technologies. CRISPR/Cas is widely used to knock-out or modify genes by inducing targeted double-strand breaks (DSBs ...
Abdellah Barakate +3 more
doaj +2 more sources
Monomer Networking Activates Recombinases [PDF]
Structure, 2006 Recombinases catalyze the DNA strand-exchange reactions of homologous recombination. The regularity of the filaments they form on DNA, though beautiful, does not explain how they work.
Wyman, C.L., Wyman, C.
core +3 more sources
Discovery and evolution of novel Cre-type tyrosine site-specific recombinases for advanced genome engineering [PDF]
, 2023 Tyrosine site-specific recombinases (Y-SSRs) are DNA editing enzymes that play a valuable role for the manipulation of genomes, due to their precision and versatility.
Jelicic, Milica
core +5 more sources
Prediction of designer-recombinases for DNA editing with generative deep learning [PDF]
Site-specific tyrosine-type recombinases are effective tools for genome engineering, with the first engineered variants having demonstrated therapeutic potential.
Schmitt, Lukas Theo
core +5 more sources
Computational characterization of recombinase circuits for periodic behaviors
iScience, 2023 Summary: Recombinases are site-specific proteins found in nature that are capable of rearranging DNA. This function has made them promising gene editing tools in synthetic biology, as well as key elements in complex artificial gene circuits implementing ...
Judith Landau +3 more
doaj +1 more source
Gene stacking by recombinases [PDF]
Plant Biotechnology Journal, 2015 SummaryEfficient methods of stacking genes into plant genomes are needed to expedite transfer of multigenic traits to crop varieties of diverse ecosystems. Over two decades of research has identified several DNA recombinases that carryout efficient cis and trans recombination between the recombination sites artificially introduced into the plant ...
Vibha, Srivastava, James, Thomson
openaire +2 more sources
Molecules, 2023 RecA family recombinases are the core enzymes in the process of homologous recombination, and their normal operation ensures the stability of the genome and the healthy development of organisms.
Yue Pan +4 more
doaj +1 more source
Frontiers in Neuroanatomy, 2017 Central noradrenergic neurons, collectively defined by synthesis of the neurotransmitter norepinephrine, are a diverse collection of cells in the hindbrain, differing in their anatomy, physiological and behavioral functions, and susceptibility to disease
Nicholas W. Plummer +4 more
doaj +1 more source