Results 211 to 220 of about 176,842 (263)

ECM Stiffness-Induced Redox Signaling Enhances Stearoyl Gemcitabine Efficacy in Pancreatic Cancer. [PDF]

open access: yesCancers (Basel)
Zhao S   +10 more
europepmc   +1 more source

The absence of Peroxiredoxin-1 in human pancreatic ductal adenocarcinoma (PDAC) markedly reduces cell survival and tumor growth when coupled with the inhibition of Ref-1 redox signaling. [PDF]

open access: yesRedox Biol
Kiran S   +11 more
europepmc   +1 more source

Redox signaling

Molecular and Cellular Biochemistry, 2002
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have recently been shown to be involved in a multiplicity of physiological responses through modulation of signaling pathways. Some of the specific signaling components altered by reactive oxygen and nitrogen species (RONS) have begun to be identified.
Henry Jay, Forman   +2 more
openaire   +2 more sources

Homocysteine and Redox Signaling

Antioxidants & Redox Signaling, 2005
Homocysteine is a thiol-containing amino acid that has gained notoriety because its elevation in the plasma is correlated with complex and multifactorial diseases, including cardiovascular diseases, neurodegenerative diseases, and neural tube defects.
Cheng-Gang, Zou, Ruma, Banerjee
openaire   +2 more sources

Nuclear Redox Signaling

Antioxidants & Redox Signaling, 2010
Reactive oxygen species have been described to modulate proteins within the cell, a process called redox regulation. However, the importance of compartment-specific redox regulation has been neglected for a long time. In the early 1980s and 1990s, many in vitro studies introduced the ...
Margarete, Lukosz   +5 more
openaire   +2 more sources

Redox signaling in macrophages

Molecular Aspects of Medicine, 2001
Macrophages are phagocytic cells that produce and release reactive oxygen species (ROS) in response to phagocytosis or stimulation with various agents. The enzyme responsible for the production of superoxide and hydrogen peroxide is a multi-component NADPH oxidase that requires assembly at the plasma membrane to function as an oxidase.
H J, Forman, M, Torres
openaire   +2 more sources

Selenium and redox signaling

Archives of Biochemistry and Biophysics, 2017
Selenium compounds that contain selenol functions or can be metabolized to selenols are toxic via superoxide and H2O2 generation, when ingested at dosages beyond requirement. At supra-nutritional dosages various forms of programmed cell death are observed.
Regina, Brigelius-Flohé   +1 more
openaire   +2 more sources

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