Results 101 to 110 of about 4,058,802 (278)

Annona squamosa: Phytochemical Fingerprinting, Health‐Improving Traits, and Functional Applications

Food Chemistry International, EarlyView.
Annona squamosa (custard apple) is a nutrient‐rich fruit containing diverse bioactive phytochemicals (e.g., acetogenins, flavonoids, and alkaloids) that contribute to multiple health benefits, including antioxidant, antihyperlipidemic, and antimicrobial activities, highlighting its potential as a functional food and medicinal resource.
Mohamed Fawzy Ramadan, Jumanah Reda Kurdi, Manar Yahya Alzahrani, Asmaa Ibrahim Alshaikhi, Jumanah Samir Hazzazi   +4 more
wiley   +1 more source

Role of the Amino Acid 45 Residue in Reduced Folate Carrier Function and Ion-Dependent Transport as Characterized by Site-Directed Mutagenesis

, 2020
In previous reports, an E45K mutation in reduced folate carrier (RFC1) resulted in marked substrate-specific changes in folate binding and the induction of an obligatory inorganic anion requirement for carrier function.
Jun Wang, PI Feng Gao, Rongbao Zhao, I David Goldman   +3 more
core  

Internalization of methotrexate conjugates by folate receptor-α [PDF]

, 2018
The folate antagonist methotrexate is a cytotoxic drug used in the treatment of several cancer types. Methotrexate entry into the cell is mediated by two main transport systems: the reduced folate carrier and membrane-associated folate receptors.
Azóia, Nuno G., Jennifer Noro, Passos, M., Antunes, Egipto, Eugénia Nogueira, Marisa P. Sárria, Ana Loureiro, Artur Cavaco-Paulo, Guimarães, Diana Isabel Pereira, Alexandra Rollett, Nogueira, E., Nuno G. Azoia, Diana Guimarães, Cavaco-Paulo, Artur, Loureiro, Ana, Georg Guebitz, Egipto Antunes, Rollett, Alexandra, Guebitz, Georg M.   +18 more
core   +1 more source

Pumpkin and chia seeds as functional foods and their application in different food products: A review

Food Biomacromolecules, EarlyView.
Abstract Functional foods have gained increasing attention for their capacity to promote health and reduce chronic‐disease risk beyond basic nutrition. Among plant‐based functional ingredients, pumpkin (Cucurbita spp.) and chia (Salvia hispanica L.) seeds are nutrient‐dense sources of proteins, unsaturated fatty acids, dietary fiber, tocopherols ...
Fatima Urooj, Fatima Javed, Abdul Mueez Ahmad, Laiba Younas, Sadia Ansar, Sumbal Raana, Muhammad Abdullah, Rimsha Amjad, Kashaf Basharat   +8 more
wiley   +1 more source

Folate malabsorption is associated with down-regulation of folate transporter expression and function at colon basolateral membrane in rats

, 2011
Folates, an essential component (important B vitamin) in the human diet, are involved in many metabolic pathways, mainly in carbon transfer reactions such as purine and pyrimidine biosynthesis and amino acid interconversions.
Krishan Lal Khanduja, Jyotdeep Kaur, Abid Hamid, Nissar Ahmad Wani   +3 more
core   +1 more source

Structural, physicochemical, and techno‐functional properties of ultrasound‐treated chickpea starch

Food Biomacromolecules, EarlyView.
Abstract This study investigated the effects of ultrasonication duration (10, 20, 30, and 40 min) on the physicochemical, functional, structural, thermal, and rheological properties of chickpea starch. Ultrasonication significantly enhanced water absorption capacity (WAC) and oil absorption capacity (OAC), with maximum values observed for U40 (2.13 g/g
Sakshi Singh, Mehvish Habib, Shumaila Jan, Kulsum Jan, Suhaib Hasan, Khalid Bashir   +5 more
wiley   +1 more source

Neuroprotective role of pyrroloquinoline quinone in folate deficiency-induced blood-brain barrier disruption

Fluids and Barriers of the CNS
Healthy neurodevelopment requires adequate folates (vitamin B9), which are critical for key biosynthetic and homeostatic processes in the central nervous system (CNS).
Sara Aboulhassane, Vishal Sangha, Md. Tozammel Hoque, Reina Bendayan   +3 more
doaj   +1 more source

[Association between maternal reduced folate carrier gene polymorphisms and congenital heart disease in offspring: a case-control study]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi, 2021
Qin JB, Sheng XQ, Wang TT, Huang P, Li YH, Luo L, Liu YP, Diao JY, Zhu P.   +8 more
europepmc   +1 more source

Physicochemical, Functional, and Health‐Promoting Properties of Processed Nettle (Urtica Dioica) Leaves: A Review

Future Postharvest and Food, EarlyView.
Stinging nettle (Urtica dioica L.) leaves are a nutrient‐dense source of proteins, dietary fiber, chlorophylls, carotenoids, and phenolic compounds. Processing technologies enable the production of powders and extracts for incorporation into bakery, beverage, dairy, and nutraceutical products; however, challenges remain regarding sensory quality ...
Mary Nkongho Tanyitiku, Rakshya Pandit, Mihiri Vanniarachchy   +2 more
wiley   +1 more source

Folate gene polymorphisms CBS 844ins68 and RFC1 A80G and risk of Down syndrome offspring in young Iranian women: A cross-sectional study

International Journal of Reproductive BioMedicine
Background: Cytogenetics and association studies showed that folate gene polymorphisms can increase the risk of chromosomal nondisjunction and aneuploidies. The folate-metabolizing gene polymorphisms in Down syndrome mothers (DSM) have been assessed in a
Neda Farajnezhad, Pegah Ghandil, Maryam Tahmasebi-Birgani, Javad Mohammadi-Asl   +3 more
doaj   +1 more source