Results 91 to 100 of about 4,058,802 (278)

Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex

BMC Genomics, 2008
Background The reduced folate carrier (RFC1) is an integral membrane protein and facilitative anion exchanger that mediates delivery of 5-methyltetrahydrofolate into mammalian cells.
Bauer Linda K, Eudy James D, van Waes Michael, Wilberding Justin, Smith Lynette M, Maddox Joyce R, Gelineau-van Waes Janee, Finnell Richard H   +7 more
doaj   +1 more source

folate

, 2015
comparison of folate vs.
Azita Hekmatdoost (825771)
core   +1 more source

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

ChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi, Adejoke D. Osinubi, Abosede A. Badeji   +2 more
wiley   +1 more source

Folate-conjugated nanoparticles as a potent therapeutic approach in targeted cancer therapy.

, 2015
The selective and efficient drug delivery to tumor cells can remarkably improve different cancer therapeutic approaches. There are several nanoparticles (NPs) which can act as a potent drug carrier for cancer therapy.
Mehdi Yousefi (12201526), Behdokht Bahrami (19973037), Farhad Jadidi-Niaragh (7385609), Sanam Sadreddini (19969821), Ghasem Ghalamfarsa (19969818), Mousa Mohammadnia-Afrouzi (8505978), Yaghoub Yazdani (8961428), Mohammad Hojjat-Farsangi (400459), Peyman Bakhshaei (19973040)   +8 more
core   +1 more source

Association of and gene polymorphisms with methotrexate efficacy and toxicity in Chinese Han patients with rheumatoid arthritis

Journal of International Medical Research, 2020
Objective The objective was to explore the association of methylene tetrahydrofolate reductase ( MTHFR ) C667T and A1298C and reduced folate carrier 1 ( RFC-1 ) A80G single nucleotide polymorphisms (SNP) with rheumatoid arthritis (RA) and efficacy and ...
Shengli Wang, Shuguang Zuo, Zhigang Liu, Xinying Ji, Zhenqiang Yao, Xinchun Wang   +5 more
doaj   +1 more source

The Roles of Reduced Folate Carrier-1 (RFC1) A80G (rs1051266) Polymorphism in Congenital Heart Disease: A Meta-Analysis. [PDF]

Med Sci Monit, 2021
Yi K, Ma YH, Wang W, Zhang X, Gao J, He SE, Xu XM, Ji M, Guo WF, You T.   +9 more
europepmc   +1 more source

Associations of common polymorphisms in the thymidylate synthase, reduced folate carrier and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase genes with folate and homocysteine levels and venous thrombosis risk.

, 2007
Item does not contain fulltextBACKGROUND: Folate is important in purine and thymidylate synthesis and, via homocysteine remethylation, facilitates S-adenosylmethionine-dependent transmethylation.
Gellekink, H., Heijer, M. den, Blom, H.J.   +2 more
core   +1 more source

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

Developmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard, Lauren Clarissa Tang, Beatrix Ueberheide, Lisa A. Taneyhill   +3 more
wiley   +1 more source

Haem and folate transport by proton-coupled folate transporter/haem carrier protein 1 (SLC46A1)

, 2008
Haem carrier protein 1 (HCP1) was originally identified and characterised as a mammalian haem transporter. However, recent evidence has shown that it is also a proton-coupled folate transporter (PCFT) and mutations in the gene cause hereditary folate ...
Abas H. Laftah, Latunde-Dada, Gladys O, Hider, Robert C, Robert J. Simpson, Gladys O. Latunde-Dada, McKie, Andrew T, Robert C. Hider, Laftah, Abas H, Sarah Fakih, Simpson, Robert J, Fakih, Sarah, Andrew T. McKie   +11 more
core   +1 more source

Interface‐Engineered MXene/g‐C3N4 Heterostructures for Energy and Environmental Applications

EcoEnergy, EarlyView.
This review highlights how interface engineering in MXene/g‐C3N4 heterostructures regulates charge transfer, band alignment, and surface chemistry, enabling broad applications in photocatalytic conversion, environmental remediation, energy storage, and multifunctional sensing/therapy. ABSTRACT Two‐dimensional MXene/g‐C3N4 heterostructures have recently
Feng Wang, Geng Liu, Xiaoqiang An
wiley   +1 more source