Results 71 to 80 of about 4,058,802 (278)

Blood‐Based Biomarkers in Alzheimer's Disease: Advances in Detection Technologies and Clinical Applications

open access: yesAGING MEDICINE, EarlyView.
Blood‐based biomarkers are emerging as accessible tools for Alzheimer's disease screening, diagnosis, risk stratification, and longitudinal monitoring. This review summarizes major biomarkers, including Aβ42/Aβ40, phosphorylated tau species, NfL, GFAP, genetic risk markers, and exploratory inflammatory, synaptic, and proteomic candidates.
Shuangshuang Li, Lin Huang, Qihao Guo
wiley   +1 more source

Rapid Determination of Membrane Transport Parameters in Adherent Cells

open access: yesBioTechniques, 2000
Reported here is a new method that permits rapid (approximately 5 s) determinations of membrane transport phenomena in cells grown in monolayers at the base of 17-mm glass scintillation vials.
Karim A. Sharif, I. David Goldman
doaj   +1 more source

Folate receptor alpha and reduced folate carrier in endometrial cancer

open access: yes, 2012
published_or_final_version ; Pathology ; Master ; Master of Medical ...
openaire   +2 more sources

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

open access: yesAdvanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang   +12 more
wiley   +1 more source

Folates in berries [PDF]

open access: yes, 2003
Folate concentrations in berries and berry products were investigated, determining folate retention from raw material to the final product. Folate content was quantified using a modified and systematically evaluated radioprotein-binding assay (RPBA). The
Strålsjö, Lena
core   +1 more source

Simplified overview of folate metabolism pathway, highlighting enzymes with polymorphisms investigated in this study.

open access: yes, 2013
MTHFR, methylene tetrahydrofolate reductase; MTR, methionine synthase; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine; MTRR, methionine synthase reductase; THF, tetrahydrofolate. RFC, the reduced folate carrier.
Guanglian Xiong (399244)   +9 more
core   +1 more source

Efficient delivery of methotrexate to MDA-MB-231 breast cancer cells by a pH-responsive ZnO nanocarrier

open access: yesScientific Reports, 2023
Methotrexate (MTX), an efficient chemotherapy medication is used in treating various malignancies. However, the breast cancer cell line MDA-MB-231 has developed resistance to it due to low levels of the MTX transport protein, and reduced folate carrier ...
Jiko Raut   +5 more
doaj   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

open access: yesAngewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean   +3 more
wiley   +1 more source

EFFECT OF SLC19A1 GENE POLYMORPHISM AND HAPLOTYPES ON IDIOPATHIC RECURRENT PREGNANCY LOSS AMONG WOMEN IN DUHOK CITY

open access: yesScience Journal of University of Zakho
Recurrent pregnancy loss (RPL) affects 1-2% of women of reproductive age and is defined as two or more consecutive losses before 20 weeks of gestation. Idiopathic RPL, which has no known etiology, is increasingly linked to genetic factors, particularly ...
Hozheen Darweesh, Adil Abozaid Eissa
doaj   +1 more source

The MTR A2756G polymorphism is associated with an increase of plasma homocysteine concentration in Brazilian individuals with Down syndrome

open access: yesBrazilian Journal of Medical and Biological Research, 2008
Individuals with Down syndrome (DS) present decreased homocysteine (Hcy) concentration, reflecting a functional folate deficiency secondary to overexpression of the cystathionine ß-synthase gene.
J.M Biselli   +4 more
doaj  

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