Results 161 to 170 of about 27,691 (245)

Over-Intake of Plant-Derived Antioxidants, H₂S Generation, and Reductive Stress. Comment on Manzano-Pech et al. The Chronic Elevated Consumption of <i>Hibiscus sabdariffa</i> Linnaeus Results in Kidney Damage Associated with Excess H₂S. <i>Int. J. Mol. Sci.</i> 2026, <i>27</i>, 2190. [PDF]

Int J Mol Sci
Nguyen JT, Pham PP, Yan LJ.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Ursodeoxycholic acid prompts glycolytic dominance, reductive stress and epithelial-to-mesenchymal transition in ovarian cancer cells through NRF2 activation. [PDF]

Cell Death Discov
Sipos A, Kerekes É, Szeőcs D, Szarvas F, Schwarcz S, Tóth E, Ujlaki G, Mikó E, Bai P.   +8 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Adaptive changes in tumor cells in response to reductive stress. [PDF]

Biochem Pharmacol
Zhang L, Zhang J, Ye ZW, Muhammad A, Li L, Culpepper JW, Townsend DM, Tew KD.   +7 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Reply to Nguyen et al. Over-Intake of Plant-Derived Antioxidants, H₂S Generation, and Reductive Stress. Comment on "Manzano-Pech et al. The Chronic Elevated Consumption of <i>Hibiscus sabdariffa</i> Linnaeus Results in Kidney Damage Associated with Excess H₂S. <i>Int. J. Mol. Sci.</i> 2026, <i>27</i>, 2190". [PDF]

Int J Mol Sci
Manzano-Pech L, Soto ME, Castrejón-Tellez V, Soria-Castro E, Guarner-Lans V, Caballero-Chacón S, Martínez-Memije R, Torres-Narváez JC, El-Hafidi M, Pérez-Torres I.   +9 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Reductive Stress-Induced Mitochondrial Dysfunction and Cardiomyopathy. [PDF]

Oxid Med Cell Longev, 2020
Ma WX, Li CY, Tao R, Wang XP, Yan LJ.
europepmc   +1 more source