Results 31 to 40 of about 28,838 (266)
Reductive stress in mitochondria isolated from the carotid body of type 1 diabetic male Wistar rats [PDF]
Physiological ReportsThe carotid body (CB) senses changes in arterial O2 partial pressure (pO2) and glucose levels; therefore, it is key for the detection of hypoxia and hypoglycemia. The CB has been suggested to detect pO2 through an increase in reactive oxygen species (ROS)
Hector R. Tejeda‐Chavez +5 more
doaj +2 more sources
Antioxidants, 2020 Oxidative stress based on mitochondrial dysfunction is assumed to be the principal molecular mechanism for the pathogenesis of many neurodegenerative disorders.
Masamichi Ikawa +3 more
doaj +2 more sources
VHL-deficiency leads to reductive stress in renal cells. [PDF]
Free Radic Biol Med, 2023 Heritable renal cancer syndromes (RCS) are associated with numerous chromosomal alterations including inactivating mutations in von Hippel-Lindau (VHL) gene. Here we identify a novel aspect of the phenotype in VHL-deficient human renal cells.
Vellama H +14 more
europepmc +5 more sources
Identification of transcriptome signature for myocardial reductive stress
Redox Biology, 2017 The nuclear factor erythroid 2 like 2 (Nfe2l2/Nrf2) is a master regulator of antioxidant gene transcription. We recently identified that constitutive activation of Nrf2 (CaNrf2) caused reductive stress (RS) in the myocardium.
Justin M. Quiles +5 more
doaj +2 more sources
Redox Biochemistry and Chemistry, 2023 Cellular respiration is highly regulated, changes dynamically in response to the microenvironment of individual cells and during differentiation and differs between cell and tissue types.
M.V. Berridge, P.M. Herst, C. Prata
doaj +2 more sources
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer [PDF]
Cell Metabolism, 2023 Maolin Ge
exaly +3 more sources
The NLRP1 and CARD8 inflammasomes detect reductive stress [PDF]
Cell Reports, 2023 Qinghui Wang +2 more
exaly +2 more sources
FermentationDespite being frequently encountered, the effect of oxidative or reductive stress on the intracellular metabolism and the response of the intracellular metabolome of yeasts is severely understudied.
Burcu Şirin Kaya, Emrah Nikerel
doaj +2 more sources
Reductive Stress-Induced Mitochondrial Dysfunction and Cardiomyopathy. [PDF]
Oxid Med Cell Longev, 2020 The goal of this review was to summarize reported studies focusing on cellular reductive stress-induced mitochondrial dysfunction, cardiomyopathy, dithiothreitol- (DTT-) induced reductive stress, and reductive stress-related free radical reactions ...
Ma WX, Li CY, Tao R, Wang XP, Yan LJ.
europepmc +2 more sources
Obesity, Chronic Stress, and Stress Reduction
Gastroenterology Clinics of North America, 2023 The obesity epidemic is caused by the misalignment between human biology and the modern food environment, which has led to unhealthy eating patterns and behaviors and an increase in metabolic diseases. This has been caused by the shift from a "leptogenic" to an "obesogenic" food environment, characterized by the availability of unhealthy food and the ...
Goens, Donald +4 more
openaire +3 more sources