Results 31 to 40 of about 27,691 (245)

Oxidative Homeostasis Regulates the Response to Reductive Endoplasmic Reticulum Stress through Translation Control

open access: yesCell Reports, 2016
Reductive stress leads to the loss of disulfide bond formation and induces the unfolded protein response of the endoplasmic reticulum (UPRER), necessary to regain proteostasis in the compartment.
Shuvadeep Maity   +10 more
doaj   +1 more source

Induction of Intracellular Reductive Stress with a Photoactivatable Phosphine Probe

open access: yesCHIMIA, 2018
Reductive stress is a condition present in cells that have an increased concentration of reducing species, and it has been associated with a number of pathologies, such as neurodegenerative diseases and cancer.
Alina Tirla, Pablo Rivera-Fuentes
doaj   +1 more source

Beyond Antioxidant Activity: Redox Properties of Catechins May Affect Changes in the DNA Methylation Profile—The Example of SRXN1 Gene

open access: yesAntioxidants, 2023
The role of catechins in the epigenetic regulation of gene expression has been widely studied; however, if and how this phenomenon relates to the redox properties of these polyphenols remains unknown.
Patrycja Jakubek   +8 more
doaj   +1 more source

Reactivity of non-organometallic ruthenium(II) polypyridyl complexes and their application as catalysts for hydride transfer reactions

open access: yesFrontiers in Chemistry, 2023
Recently, we investigated the substitution behavior of a series of ruthenium(II) complexes of the general formula [RuII(terpy)(N∧N)Cl]Cl, where terpy = 2,2′:6′,2″-terpyridine, N∧N = bidentate ligand, in aqueous solutions.
Marta Chrzanowska   +3 more
doaj   +1 more source

On Males, Antioxidants and Infertility (MOXI): Certitudes, Uncertainties and Trends

open access: yesAntioxidants, 2023
Male infertility (MI) involves various endogenous and exogenous facts. These include oxidative stress (OS), which is known to alter several physiological pathways and it is estimated to be present at high levels in up to 80% of infertile men. That is why
Manuel Alfaro Gómez   +7 more
doaj   +1 more source

Psychophysiologic stress reduction in surgery [PDF]

open access: yesSurgical Endoscopy, 2012
We read with interest the paper entitled Effects of Intraoperative Breaks on Mental and Somatic Operator Fatigue. This paper describes a randomized clinical trial authored by Engelmann and colleagues, who noted that ‘‘work breaks during complex laparoscopic surgery can reduce psychological stress and preserve performance without prolongation of the ...
Annika, Rieger, Regina, Stoll
openaire   +2 more sources

FASN deficiency induces a cytosol-to-mitochondria citrate flux to mitigate detachment-induced oxidative stress

open access: yesCell Reports, 2023
Summary: Fatty acid synthase (FASN) maintains de novo lipogenesis (DNL) to support rapid growth in most proliferating cancer cells. Lipogenic acetyl-coenzyme A (CoA) is primarily produced from carbohydrates but can arise from glutamine-dependent ...
Wenting Dai   +5 more
doaj   +1 more source

Redox Balance in Male Infertility: Excellence through Moderation—“Μέτρον ἄριστον”

open access: yesAntioxidants, 2021
Male infertility, a relatively common and multifactorial medical condition, affects approximately 15% of couples globally. Based on WHO estimates, a staggering 190 million people struggle with this health condition, and male factor is the sole or ...
Evangelos N. Symeonidis   +12 more
doaj   +1 more source

More than Just Antioxidants: Redox-Active Components and Mechanisms Shaping Redox Signalling Network

open access: yesAntioxidants, 2022
The concept of oxidative stress as a condition underlying a multitude of human diseases has led to immense interest in the search for antioxidant-based remedies.
Monika Kuczyńska   +2 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

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