Oxidative Stress, Reductive Stress and Antioxidants in Vascular Pathogenesis and Aging [PDF]
Antioxidants, 2023 This review is focused on the mechanisms that regulate health, disease and aging redox status, the signal pathways that counteract oxidative and reductive stress, the role of food components and additives with antioxidant properties (curcumin ...
Mitko Mladenov +10 more
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Reductive stress—a common metabolic feature of obesity and cancer [PDF]
Acta Pharmaceutica Sinica BReductive stress, characterized by rising level of NADH (nicotinamide adenine dinucleotide) for a status of NADH/NAD+ ratio elevation, has been reported in obesity and cancer.
Man Luo, Xiwen Ma, Jianping Ye
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Impaired Renal Function Due to Reductive Stress Is Associated with Excessive Consumption of Hibiscus sabdariffa Linnaeus [PDF]
AntioxidantsReductive stress (RS) results from the overactivity of the enzymatic and non-enzymatic antioxidant systems and from excess antioxidant agents that neutralize reactive oxygen species.
Linaloe Manzano-Pech +11 more
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Tandem Mass Tagging Based Identification of Proteome Signatures for Reductive Stress Cardiomyopathy [PDF]
Frontiers in Cardiovascular Medicine, 2022 Nuclear factor erythroid 2-related factor 2 (NRF2), a redox sensor, is vital for cellular redox homeostasis. We reported that transgenic mice expressing constitutively active Nrf2 (CaNrf2-TG) exhibit reductive stress (RS).
Sini Sunny +10 more
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Reductive stress in mitochondria isolated from the carotid body of type 1 diabetic male Wistar rats [PDF]
Physiological ReportsThe carotid body (CB) senses changes in arterial O2 partial pressure (pO2) and glucose levels; therefore, it is key for the detection of hypoxia and hypoglycemia. The CB has been suggested to detect pO2 through an increase in reactive oxygen species (ROS)
Hector R. Tejeda‐Chavez +5 more
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Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress [PDF]
BMC Microbiology, 2023 Background Mycobacterium tuberculosis (Mtb) forms physiologically relevant biofilms harboring drug-tolerant bacteria. This observation has brought the study of mycobacterial biofilms to the forefront of tuberculosis research.
Parminder Singh Mavi +2 more
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NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer. [PDF]
Cell Metab, 2023 Weiss-Sadan T +26 more
europepmc +3 more sources
Thiol reductive stress activates the hypoxia response pathway. [PDF]
EMBO J, 2023 Ravi, Kumar A, Bhattacharyya S, Singh J.
europepmc +2 more sources
Structural basis and regulation of the reductive stress response. [PDF]
Cell, 2021 Manford AG +12 more
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Obesity, Chronic Stress, and Stress Reduction
Gastroenterology Clinics of North America, 2023 The obesity epidemic is caused by the misalignment between human biology and the modern food environment, which has led to unhealthy eating patterns and behaviors and an increase in metabolic diseases. This has been caused by the shift from a "leptogenic" to an "obesogenic" food environment, characterized by the availability of unhealthy food and the ...
Goens, Donald +4 more
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