Results 131 to 140 of about 8,117,731 (311)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Gene expression reference

open access: yes, 2019
Species specific reference for downstream mapping (for estimating gene expression with RSEM) consisting of 15,074 protein coding regions annotated for Pogona vitticeps (the closest con-familial species for which a fully annotated genome is available)
Claire McLean (3552074)   +11 more
core   +1 more source

EndoGeneAnalyzer: A tool for selection and validation of reference genes

open access: yesPLOS ONE
The selection of proper reference genes is critical for accurate gene expression analysis in all fields of biological and medical research, mainly because there are many distinctions between different tissues and specimens. Given this variability, even in known classic reference genes, demands of a comprehensive analysis platform is needed to identify ...
Eliel Barbosa Teixeira   +5 more
openaire   +3 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Definition of Reference 2021

open access: yes, 2021
To update the 2008 version and to extend the conception of reference work beyond the ...
Reference Services Section (RSS) Executive Committee
core  

Validation of Stable Reference Genes for RT-qPCR Normalization in Oxycetonia jucunda (Coleoptera: Scarabaeidae)

open access: yesInsects
The polyphagous pest Oxycetonia jucunda Faldermann can cause substantial damage to a range of economically important crops, with the adult beetles feeding directly on floral tissues and young leaves. RT-qPCR is widely used to analyze gene expression, for
Shi-Hang Zhao   +7 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

The Gene Ontology's Reference Genome Project: A Unified Framework for Functional Annotation across Species

open access: yes, 2009
Complete functional annotation of genomes is a powerful tool for researchers; however, such annotation is a time-consuming task limited by the availability of experimental data.
Reference Genome Group, Pascale Gaudet
core   +1 more source

Screening and Identification of Reference Genes for Paracarophenax alternatus

open access: yesInsects
In this study, we focused on the screening and identification of reference genes for Paracarophenax alternatus Xu and Zhang. The laboratory population was used as the laboratory population, and samples were collected from mites at four different stages, including physogastry, viviparous, 5 d viviparous and phoresy.
Yangming Zhang   +6 more
openaire   +2 more sources

Screening of Reference Genes for Quantitative Real-time PCR in Globba spp.

open access: yesGuangdong nongye kexue
【Objective】Screening for stable reference genes that are applicable to the study of different varieties of Globba spp. bracts and different tissue parts of G.
Lishan HUANG   +8 more
doaj   +1 more source

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